apoptosis-inducing factor, mitochondrion-associated, 2

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Synonym

AMID, PRG3, RP11-367H5.2, p53-responsive gene 3 protein, FLJ14497

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:0.75 cerebellum:- brain stem:1.15 corpus callosum/glia:0.91 pineal gland:0.97 peripheral nerve:- spine:1.15 retina:- eye:- artery/aorta:2.53 vein:2.80 lymphnode:1.67 peripheral blood:- spleen:1.76 thymus:0.42 bone marrow:- adipose:3.37 bone:- skin:-
RNA-seq cerebrum:0.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.43 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.97 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:1.56 placenta:1.66 prostate:1.88 ovary:1.98 testis:1.34 heart:2.54 muscle:1.97 esophagus:1.95 stomach:- intestine:2.25 colon:2.09     liver/hepato:2.69    lung:2.02 bladder:2.46 kidney:2.30 pituitary:0.76 thyroid/parathyroid:2.25 adrenal gland:- pancreas:0.58 breast:3.69 salivary:1.67
RNA-seq uterus:- placenta:- prostate:2.81 ovary:2.47 testis:1.99 heart:1.01 muscle:1.72 esophagus:- stomach:- intestine:- colon:1.97     liver/hepato:2.62        lung:2.14    bladder:- kidney:2.64 pituitary:- thyroid/parathyroid:3.25 adrenal gland:1.97 pancreas:- breast:5.03 salivary:-

Gene Information

IDs

Refseq ID NM_032797
Gene ID 84883
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000042286
GTEx ID ENSG00000042286

Orthologous Gene

Mouse[3]  NM_001039194, NM_153779, NM_178058
Rat[2]  NM_001139483, NM_153779, NM_178058

Chromosomal Region

10q22.1  [71,857,979  -  71,892,690]

Gene Family (Interpro ID)

IPR003042  Aromatic-ring hydroxylase-like
IPR013027  FAD-dependent pyridine nucleotide-disulphide oxidoreductase
IPR000103  Pyridine nucleotide-disulphide oxidoreductase, class-II

Link to Pubmed  (Pubmed ID)

10441517
11980907
12135761
12477932
14702039
14741744
15164054
15273740
15342556
15489334
15958387
17347867
17711848
19270026
20635389
20877624
21139048
21890473
21906983
22623531
23000965

Gene Ontology  (GO ID)

Biological Process

GO:0008637  apoptotic mitochondrial changes
GO:0030261  chromosome condensation
GO:0006917  induction of apoptosis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016021  integral to membrane
GO:0005811  lipid particle
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion

Molecular Function

GO:0003677  DNA binding
GO:0004174  electron-transferring-flavoprotein dehydrogenase activity
GO:0050660  FAD binding