phospholipase A2, group IVC (cytosolic, calcium-independent)

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Synonym

Cytosolic phospholipase A2 gamma precursor, Phospholipase A2 group IVC, CPLA2-gamma, cPLA2-gamma, DKFZp586C0423, PLA2G4C

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:149.30 cerebellum:277.10 brain stem:- corpus callosum/glia:320.80 pineal gland:- peripheral nerve:- spine:- retina:237.30 eye:70.50 artery/aorta:299.80 vein:66.60 lymphnode:- peripheral blood:72.90 spleen:472.70 thymus:12.90 bone marrow:- adipose:282.30 bone:76.80 skin:38.40
GeneChip cerebrum:7.51 cerebellum:7.10 brain stem:7.64 corpus callosum/glia:8.24 pineal gland:- peripheral nerve:6.49 spine:7.49 retina:- eye:- artery/aorta:6.61 vein:6.68 lymphnode:6.86 peripheral blood:- spleen:7.31 thymus:5.12 bone marrow:4.72 adipose:5.91 bone:- skin:5.63
CAGE cerebrum:3.42 cerebellum:- brain stem:4.15 corpus callosum/glia:4.17 pineal gland:3.63 peripheral nerve:- spine:3.88 retina:- eye:- artery/aorta:2.88 vein:3.06 lymphnode:1.82 peripheral blood:- spleen:2.65 thymus:1.46 bone marrow:- adipose:2.38 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.43 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:127.60 placenta:47.40 prostate:56.30 ovary:74.50 testis:21.60 heart:102.20 muscle:80.40 esophagus:342.80 stomach:21.20 intestine:129.60 colon:17     liver/hepato:-        lung:83.10    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:203.10 pancreas:17.80 breast:46.50 salivary:-
GeneChip uterus:6 placenta:5.75 prostate:5.73 ovary:5.19 testis:5.10 heart:6.48 muscle:8.70 esophagus:6.08 stomach:5.92 intestine:6.20 colon:5.72 liver/hepato:5.95 lung:6.41 bladder:- kidney:5.58 pituitary:6.15 thyroid/parathyroid:5.91 adrenal gland:7.31 pancreas:4.90 breast:5.98 salivary:5.18
CAGE uterus:2.18 placenta:1.68 prostate:2.27 ovary:2.06 testis:1.70 heart:2.86 muscle:3.76 esophagus:1.88 stomach:- intestine:2.52 colon:1.71     liver/hepato:1.12    lung:2.30 bladder:2.14 kidney:2.15 pituitary:2.18 thyroid/parathyroid:1.48 adrenal gland:- pancreas:1.42 breast:1.36 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.01 testis:0.37 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.31        lung:0.00    bladder:- kidney:0.99 pituitary:- thyroid/parathyroid:0.00 adrenal gland:1.26 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001159322
Gene ID 8605
Unigene ID Hs.631562
Probe set ID 209785_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105499
GTEx ID ENSG00000105499

Orthologous Gene

Mouse[2]  NM_001004762, NM_001168504
Rat[2]  NM_001145982, NM_001168504

Chromosomal Region

19q13.33  [48,551,100  -  48,614,109]

Gene Family (Interpro ID)

IPR016035  Acyl transferase/acyl hydrolase/lysophospholipase
IPR002642  Lysophospholipase, catalytic domain

Link to Pubmed  (Pubmed ID)

9202034
9377118
9705332
9745929
10085124
10708517
11958371
12039969
12396716
12477932
12502717
14529291
14702039
15489334
15788676
15908428
15944408
16181776
16882668
17213206
17417066
17459165
18686860
19501189
19913121
20016400
20056178
20452986
20628086
21184677
21600875
21832049
22108055
22878031
23025307

Gene Ontology  (GO ID)

Biological Process

GO:0019369  arachidonic acid metabolic process
GO:0046474  glycerophospholipid biosynthetic process
GO:0046475  glycerophospholipid catabolic process
GO:0006954  inflammatory response
GO:0007567  parturition
GO:0006644  phospholipid metabolic process

Cellular Component

GO:0005829  cytosol
GO:0005789  endoplasmic reticulum membrane
GO:0016020  membrane

Molecular Function

GO:0047499  calcium-independent phospholipase A2 activity
GO:0005543  phospholipid binding