TNFRSF1A-associated via death domain

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Synonym

TNFR1-associated DEATH domain protein, TRADD, TNFRSF1A-associated via death domain, MGC11078, Hs.89862

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:8.30

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:-

lymphnode:111.20

peripheral blood:-

spleen:94.50

thymus:-

bone marrow:19.70

adipose:40.30

bone:-

skin:9.60

GeneChip

cerebrum:6.92

cerebellum:6.82

brain stem:7.20

corpus callosum/glia:6.93

pineal gland:-

peripheral nerve:6.73

spine:6.93

retina:-

eye:-

artery/aorta:7.14

vein:7.21

lymphnode:7.80

peripheral blood:-

spleen:7.76

thymus:7.39

bone marrow:7.25

adipose:7.48

bone:-

skin:7.35

CAGE

cerebrum:1.63

cerebellum:-

brain stem:2.11

corpus callosum/glia:2.56

pineal gland:2.23

peripheral nerve:-

spine:1.96

retina:-

eye:-

artery/aorta:2.72

vein:2.82

lymphnode:2.99

peripheral blood:-

spleen:2.70

thymus:2.23

bone marrow:-

adipose:2.67

bone:-

skin:-

RNA-seq

cerebrum:1.35

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.66

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.76

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:7.30

prostate:78.90

ovary:-

testis:4.30

heart:51.10

muscle:-

esophagus:-

stomach:-

intestine:-

colon:33.90

liver/hepato:31.70

lung:24.40

bladder:-

kidney:104

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:44.50

breast:37.20

salivary:-

GeneChip

uterus:7.14

placenta:7.56

prostate:7.47

ovary:7.14

testis:6.47

heart:7.15

muscle:6.71

esophagus:7.66

stomach:7.62

intestine:7.33

colon:7.57

liver/hepato:7.26

lung:7.62

bladder:-

kidney:7.44

pituitary:6.98

thyroid/parathyroid:7.62

adrenal gland:7.37

pancreas:7.13

breast:7.44

salivary:7.37

CAGE

uterus:2.55

placenta:2.74

prostate:2.79

ovary:2.66

testis:1.91

heart:2.13

muscle:1.49

esophagus:2.93

stomach:-

intestine:2.63

colon:2.68

liver/hepato:2.46

lung:2.72

bladder:2.40

kidney:2.80

pituitary:1.90

thyroid/parathyroid:2.96

adrenal gland:-

pancreas:2.81

breast:2.11

salivary:2.83

RNA-seq

uterus:-

placenta:-

prostate:3.54

ovary:3.04

testis:2.33

heart:1.31

muscle:1.86

esophagus:-

stomach:-

intestine:-

colon:2.36

liver/hepato:2.34

lung:3.57

bladder:-

kidney:3.21

pituitary:-

thyroid/parathyroid:2.45

adrenal gland:3.26

pancreas:-

breast:3.08

salivary:-

IDs

Refseq ID	NM_003789
Gene ID	8717
Unigene ID	Hs.460996
Probe set ID	205641_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000102871
GTEx ID	ENSG00000102871

Orthologous Gene

Mouse[2]	NM_001033161
Rat [0]

Chromosomal Region

16q22.1 [67,188,083 - 67,193,789]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000488	Death
IPR011029	DEATH-like

GO:0006919	activation of caspase activity
GO:0006915	apoptosis
GO:0006917	induction of apoptosis
GO:0008625	induction of apoptosis via death domain receptors
GO:0051798	positive regulation of hair follicle development
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0007165	signal transduction
GO:0033209	tumor necrosis factor-mediated signaling pathway

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0005634	nucleus
GO:0043235	receptor complex

GO:0070513	death domain binding
GO:0042802	identical protein binding
GO:0019900	kinase binding
GO:0060090	molecular adaptor activity
GO:0005515	protein binding
GO:0004871	signal transducer activity

TNFRSF1A-associated via death domain

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function