tumor necrosis factor receptor superfamily, member 10a

Synonym

TRAILR1, MGC9365, death receptor-5 (DR-5), APO2, DR4, TNFRSF10A, CD261, TRAIL receptor 1, Apo2, Death receptor 4, TRAILR-1, TRAIL-R1, TNF-related apoptosis-inducing ligand receptor 1, CD261 antigen

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.60

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:60

vein:-

lymphnode:-

peripheral blood:18.20

spleen:37.80

thymus:51.50

bone marrow:78.70

adipose:-

bone:38.40

skin:9.60

GeneChip

nodata

CAGE

cerebrum:1.03

cerebellum:-

brain stem:1.20

corpus callosum/glia:0.96

pineal gland:0.71

peripheral nerve:-

spine:1.23

retina:-

eye:-

artery/aorta:1.94

vein:2.97

lymphnode:2.70

peripheral blood:-

spleen:2.63

thymus:2.21

bone marrow:-

adipose:2.55

bone:-

skin:-

RNA-seq

cerebrum:0.49

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.63

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.93

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:3.60

prostate:11.30

ovary:-

testis:-

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:-

lung:29.30

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:18.60

salivary:-

GeneChip

nodata

CAGE

uterus:2.00

placenta:1.87

prostate:1.86

ovary:1.39

testis:1.09

heart:1.98

muscle:1.54

esophagus:2.56

stomach:-

intestine:2.41

colon:2.44

liver/hepato:2.35

lung:2.26

bladder:2.00

kidney:2.47

pituitary:0.42

thyroid/parathyroid:1.87

adrenal gland:-

pancreas:2.66

breast:2.47

salivary:1.82

RNA-seq

uterus:-

placenta:-

prostate:1.53

ovary:0.51

testis:1.06

heart:0.84

muscle:0.53

esophagus:-

stomach:-

intestine:-

colon:2.05

liver/hepato:1.08

lung:2.89

bladder:-

kidney:1.27

pituitary:-

thyroid/parathyroid:1.34

adrenal gland:2.53

pancreas:-

breast:1.85

salivary:-

IDs

Refseq ID	NM_003844
Gene ID	8797
Unigene ID	Hs.591834
Probe set ID	-
Ensembl ID	ENSG00000104689
GTEx ID	ENSG00000104689

Orthologous Gene

Mouse[2]	NM_020275
Rat[1]	NM_001108873

Chromosomal Region

8p21.3 [23,047,965 - 23,082,639]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000488	Death
IPR011029	DEATH-like

GO:0006919	activation of caspase activity
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0071260	cellular response to mechanical stimulus
GO:0006917	induction of apoptosis
GO:0008625	induction of apoptosis via death domain receptors
GO:0007165	signal transduction

GO:0005035	death receptor activity
GO:0005515	protein binding
GO:0004872	receptor activity
GO:0045569	TRAIL binding
GO:0008134	transcription factor binding

tumor necrosis factor receptor superfamily, member 10a

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function