adaptor-related protein complex 1, sigma 2 subunit

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Synonym

Adaptor protein complex AP-1 sigma-1B subunit, adaptor-related protein complex 1, sigma 2 subunit, MGC:1902, SIGMA1B, Golgi adaptor HA1/AP1 adaptin sigma-1B subunit, Sigma 1B subunit of AP-1 clathrin, DC22, Adapter-related protein complex 1 sigma-1B subunit, Sigma-adaptin 1B, AP-1 complex subunit sigma-2, AP1S2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.57 cerebellum:7.71 brain stem:7.99 corpus callosum/glia:7.32 pineal gland:- peripheral nerve:8.66 spine:7.86 retina:- eye:- artery/aorta:6.71 vein:7.18 lymphnode:6.97 peripheral blood:- spleen:7.63 thymus:7.44 bone marrow:8.03 adipose:7.04 bone:- skin:6.69
CAGE cerebrum:3.67 cerebellum:- brain stem:4.13 corpus callosum/glia:3.40 pineal gland:2.75 peripheral nerve:- spine:4.00 retina:- eye:- artery/aorta:3.25 vein:3.42 lymphnode:3.02 peripheral blood:- spleen:3.73 thymus:3.25 bone marrow:- adipose:3.51 bone:- skin:-
RNA-seq cerebrum:4.62 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.63 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.42 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.11 placenta:7.47 prostate:6.37 ovary:6.60 testis:6.59 heart:8.05 muscle:8.95 esophagus:6.67 stomach:7.03 intestine:7.51 colon:6.91 liver/hepato:6.02 lung:7.27 bladder:- kidney:6.04 pituitary:6.86 thyroid/parathyroid:5.85 adrenal gland:5.92 pancreas:6.13 breast:6.29 salivary:5.21
CAGE uterus:3.92 placenta:2.84 prostate:2.93 ovary:2.75 testis:3.09 heart:3.87 muscle:3.45 esophagus:3.39 stomach:- intestine:2.60 colon:3.06     liver/hepato:2.15    lung:3.10 bladder:3.25 kidney:2.54 pituitary:3.49 thyroid/parathyroid:3.43 adrenal gland:- pancreas:1.98 breast:3.54 salivary:1.82
RNA-seq uterus:- placenta:- prostate:4.09 ovary:3.78 testis:4.50 heart:5.52 muscle:4.55 esophagus:- stomach:- intestine:- colon:5.35     liver/hepato:2.28        lung:3.84    bladder:- kidney:3.28 pituitary:- thyroid/parathyroid:4.06 adrenal gland:4.22 pancreas:- breast:4.06 salivary:-

Gene Information

IDs

Refseq ID NM_003916
Gene ID 8905
Unigene ID -
Probe set ID 203300_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000182287
GTEx ID ENSG00000182287

Orthologous Gene

Mouse[1]  NM_026887
Rat[1]  NM_001127531

Chromosomal Region

Xp22.2  [15,843,929  -  15,873,054]

Gene Family (Interpro ID)

IPR016635  Adaptor protein complex, sigma subunit
IPR000804  Clathrin adaptor, sigma subunit/coatomer, zeta subunit

Link to Pubmed  (Pubmed ID)

2040623
9733768
9736718
9811606
9811611
9882340
10398241
10966473
11031247
11222723
11252894
11463741
11694590
12215646
12477932
12486136
12836198
15489334
15569716
15681409
16253302
17186471
17617514
18336259
18428203
19149577
19322201
20594957
21139048
21762802
21890473
22103831
22939629
23077317
23678182
23705972
23756445
24797263

Gene Ontology  (GO ID)

Biological Process

GO:0019886  antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0006897  endocytosis
GO:0006886  intracellular protein transport
GO:0016044  membrane organization
GO:0006892  post-Golgi vesicle-mediated transport
GO:0050690  regulation of defense response to virus by virus
GO:0016032  viral reproduction

Cellular Component

GO:0030119  AP-type membrane coat adaptor complex
GO:0005905  coated pit
GO:0030659  cytoplasmic vesicle membrane
GO:0005829  cytosol
GO:0000139  Golgi membrane
GO:0005765  lysosomal membrane
GO:0032588  trans-Golgi network membrane

Molecular Function

GO:0008565  protein transporter activity