Rho guanine nucleotide exchange factor (GEF) 1

Synonym

SUB1.5, P115-RHOGEF, GEF1, Rho guanine nucleotide exchange factor (GEF) 1, Rho guanine nucleotide exchange factor 1, ARHGEF1, LBCL2, Sub1.5, p115-RhoGEF, 115 kDa guanine nucleotide exchange factor, p115RhoGEF

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:22.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:61.30

spine:-

retina:-

eye:23.50

artery/aorta:-

vein:133.30

lymphnode:566.20

peripheral blood:91.10

spleen:94.50

thymus:12.90

bone marrow:1239.90

adipose:80.70

bone:76.80

skin:19.20

GeneChip

cerebrum:7.19

cerebellum:7.02

brain stem:7.23

corpus callosum/glia:7.84

pineal gland:-

peripheral nerve:6.81

spine:7.27

retina:-

eye:-

artery/aorta:7.31

vein:7.40

lymphnode:9.11

peripheral blood:-

spleen:9.12

thymus:8.92

bone marrow:8.22

adipose:7.61

bone:-

skin:7.06

CAGE

cerebrum:3.33

cerebellum:-

brain stem:3.87

corpus callosum/glia:4.32

pineal gland:3.69

peripheral nerve:-

spine:3.96

retina:-

eye:-

artery/aorta:3.49

vein:4.82

lymphnode:4.64

peripheral blood:-

spleen:4.16

thymus:4.63

bone marrow:-

adipose:3.23

bone:-

skin:-

RNA-seq

cerebrum:0.25

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.48

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.74

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:14.60

prostate:45.10

ovary:74.50

testis:21.60

heart:-

muscle:-

esophagus:-

stomach:85

intestine:97.20

colon:127.20

liver/hepato:10.60

lung:39.10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:27.90

salivary:-

GeneChip

uterus:7.15

placenta:7

prostate:6.73

ovary:7.06

testis:6.42

heart:7.20

muscle:7.32

esophagus:7.32

stomach:7.67

intestine:7.37

colon:7.61

liver/hepato:7.65

lung:8.04

bladder:-

kidney:7.37

pituitary:7.24

thyroid/parathyroid:7.34

adrenal gland:7.46

pancreas:7.22

breast:7.24

salivary:7.22

CAGE

uterus:3.50

placenta:2.73

prostate:3.22

ovary:3.09

testis:2.68

heart:3.38

muscle:2.67

esophagus:3.31

stomach:-

intestine:3.45

colon:3.92

liver/hepato:2.70

lung:4.00

bladder:3.10

kidney:2.93

pituitary:3.63

thyroid/parathyroid:2.87

adrenal gland:-

pancreas:2.94

breast:3.40

salivary:2.88

RNA-seq

uterus:-

placenta:-

prostate:2.41

ovary:2.41

testis:1.32

heart:1.54

muscle:1.05

esophagus:-

stomach:-

intestine:-

colon:1.93

liver/hepato:1.89

lung:3.41

bladder:-

kidney:2.66

pituitary:-

thyroid/parathyroid:2.54

adrenal gland:5.15

pancreas:-

breast:2.59

salivary:-

IDs

Refseq ID	NM_004706
Gene ID	9138
Unigene ID	Hs.631550
Probe set ID	203055_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000076928
GTEx ID	ENSG00000076928

Orthologous Gene

Mouse[5]	NM_001130150, NM_001130151, NM_001130152, NM_001130153, NM_008488
Rat[1]	NM_021694, NM_001130151, NM_001130152, NM_001130153, NM_008488

Chromosomal Region

19q13.2 [42,387,267 - 42,411,597]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001849

Pleckstrin homology

GO:0008283	cell proliferation
GO:0050771	negative regulation of axonogenesis
GO:0048011	nerve growth factor receptor signaling pathway
GO:0050770	regulation of axonogenesis
GO:0035023	regulation of Rho protein signal transduction
GO:0007266	Rho protein signal transduction

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane

GO:0005096	GTPase activator activity
GO:0005543	phospholipid binding
GO:0005515	protein binding
GO:0005089	Rho guanyl-nucleotide exchange factor activity

Rho guanine nucleotide exchange factor (GEF) 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function