CD3e molecule, epsilon (CD3-TCR complex)

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Synonym

T-cell surface antigen T3/Leu-4 epsilon chain, T3E, CD3E, CD3e molecule, epsilon (CD3-TCR complex), TCRE

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:10.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.35

cerebellum:5.29

brain stem:5.41

corpus callosum/glia:5.33

pineal gland:-

peripheral nerve:5.54

spine:5.59

retina:-

eye:-

artery/aorta:5.90

vein:5.63

lymphnode:6.97

peripheral blood:-

spleen:6.41

thymus:8.55

bone marrow:6.66

adipose:6.04

bone:-

skin:5.66

CAGE

cerebrum:0.30

cerebellum:-

brain stem:1.13

corpus callosum/glia:1.08

pineal gland:0.35

peripheral nerve:-

spine:0.94

retina:-

eye:-

artery/aorta:2.12

vein:5.01

lymphnode:5.03

peripheral blood:-

spleen:4.23

thymus:6.90

bone marrow:-

adipose:1.66

bone:-

skin:-

RNA-seq

cerebrum:0.16

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:6.47

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.75

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:14.70

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:106.70

breast:-

salivary:-

GeneChip

uterus:5.51

placenta:5.74

prostate:5.39

ovary:5.39

testis:5.13

heart:5.65

muscle:5.48

esophagus:5.54

stomach:6.04

intestine:5.81

colon:6.07

liver/hepato:5.94

lung:5.95

bladder:-

kidney:5.53

pituitary:5.55

thyroid/parathyroid:5.41

adrenal gland:5.52

pancreas:6.21

breast:5.57

salivary:5.80

CAGE

uterus:2.02

placenta:1.32

prostate:2.13

ovary:1.68

testis:1.02

heart:0.92

muscle:0.42

esophagus:2.32

stomach:-

intestine:3.54

colon:2.69

liver/hepato:1.71

lung:3.09

bladder:2.51

kidney:2.20

pituitary:0.32

thyroid/parathyroid:1.73

adrenal gland:-

pancreas:1.21

breast:0.55

salivary:2.72

RNA-seq

uterus:-

placenta:-

prostate:2.13

ovary:1.93

testis:1.20

heart:0.40

muscle:0.34

esophagus:-

stomach:-

intestine:-

colon:1.83

liver/hepato:1.43

lung:4.24

bladder:-

kidney:0.92

pituitary:-

thyroid/parathyroid:1.38

adrenal gland:5.60

pancreas:-

breast:1.96

salivary:-

IDs

Refseq ID	NM_000733
Gene ID	916
Unigene ID	Hs.300304
Probe set ID	205456_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000198851
GTEx ID	ENSG00000198851

Orthologous Gene

Mouse[1]	NM_007648
Rat [0]

Chromosomal Region

11q23.3 [118,175,260 - 118,186,890]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_38 [5,001 - 16,596]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007166	cell surface receptor linked signal transduction
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0045879	negative regulation of smoothened signaling pathway
GO:0045060	negative thymic T cell selection
GO:0046641	positive regulation of alpha-beta T cell proliferation
GO:0050850	positive regulation of calcium-mediated signaling
GO:0032729	positive regulation of interferon-gamma production
GO:0045086	positive regulation of interleukin-2 biosynthetic process
GO:0032753	positive regulation of interleukin-4 production
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0002669	positive regulation of T cell anergy
GO:0042102	positive regulation of T cell proliferation
GO:0006461	protein complex assembly
GO:0042981	regulation of apoptosis
GO:0050776	regulation of immune response
GO:0007584	response to nutrient
GO:0007172	signal complex assembly
GO:0042110	T cell activation
GO:0031295	T cell costimulation
GO:0050852	T cell receptor signaling pathway
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0042105	alpha-beta T cell receptor complex
GO:0009897	external side of plasma membrane
GO:0001772	immunological synapse
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane
GO:0042101	T cell receptor complex

Molecular Function

GO:0046982	protein heterodimerization activity
GO:0019901	protein kinase binding
GO:0030159	receptor signaling complex scaffold activity
GO:0005057	receptor signaling protein activity
GO:0017124	SH3 domain binding
GO:0042608	T cell receptor binding
GO:0004888	transmembrane receptor activity

CD3e molecule, epsilon (CD3-TCR complex)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function