CD86 molecule

Synonym

T-lymphocyte activation antigen CD86 precursor, CD86 molecule, B7-2, B70, FUN-1, CTLA-4 counter-receptor B7.2, LAB72, Activation B7-2 antigen, BU63, CD86, MGC34413, CD28LG2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:14.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:11.80

artery/aorta:30

vein:-

lymphnode:60.70

peripheral blood:309.70

spleen:113.40

thymus:25.80

bone marrow:-

adipose:-

bone:-

skin:24

GeneChip

cerebrum:4.38

cerebellum:3.95

brain stem:4.62

corpus callosum/glia:4.89

pineal gland:-

peripheral nerve:4.72

spine:5.34

retina:-

eye:-

artery/aorta:4.40

vein:4.30

lymphnode:5.58

peripheral blood:-

spleen:5.48

thymus:4.73

bone marrow:4.75

adipose:4.88

bone:-

skin:4.34

CAGE

cerebrum:1.93

cerebellum:-

brain stem:2.68

corpus callosum/glia:2.75

pineal gland:1.92

peripheral nerve:-

spine:3.25

retina:-

eye:-

artery/aorta:2.17

vein:2.97

lymphnode:3.12

peripheral blood:-

spleen:3.50

thymus:2.36

bone marrow:-

adipose:2.86

bone:-

skin:-

RNA-seq

cerebrum:1.53

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.47

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.23

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:29.10

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:-

liver/hepato:-

lung:29.30

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:9.30

salivary:-

GeneChip

uterus:4.03

placenta:4.54

prostate:4.01

ovary:4.16

testis:4.27

heart:4.31

muscle:4.46

esophagus:4.14

stomach:4.28

intestine:4.50

colon:4.54

liver/hepato:4.48

lung:6.39

bladder:-

kidney:3.92

pituitary:4.29

thyroid/parathyroid:4.14

adrenal gland:4.40

pancreas:4.89

breast:4.34

salivary:4.05

CAGE

uterus:1.47

placenta:2.38

prostate:1.86

ovary:1.67

testis:1.13

heart:1.58

muscle:0.61

esophagus:1.56

stomach:-

intestine:2.03

colon:1.46

liver/hepato:2.17

lung:3.04

bladder:1.73

kidney:1.98

pituitary:1.52

thyroid/parathyroid:0.76

adrenal gland:-

pancreas:0.94

breast:1.36

salivary:1.39

RNA-seq

uterus:-

placenta:-

prostate:0.88

ovary:1.42

testis:0.74

heart:0.37

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:1.49

lung:2.63

bladder:-

kidney:0.47

pituitary:-

thyroid/parathyroid:0.37

adrenal gland:0.98

pancreas:-

breast:1.43

salivary:-

IDs

Refseq ID	NM_175862
Gene ID	942
Unigene ID	Hs.171182
Probe set ID	210895_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000114013
GTEx ID	ENSG00000114013

Orthologous Gene

Mouse[2]	NM_019388
Rat [0]

Chromosomal Region

3q13.33 [121,774,213 - 121,839,983]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR013106	Immunoglobulin V-set
IPR003596	Immunoglobulin V-set, subgroup

Gene Ontology (GO ID)

Biological Process

GO:0042113	B cell activation
GO:0007267	cell-cell signaling
GO:0051607	defense response to virus
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0006955	immune response
GO:0045087	innate immune response
GO:0048011	nerve growth factor receptor signaling pathway
GO:0048015	phosphoinositide-mediated signaling
GO:0008284	positive regulation of cell proliferation
GO:0045086	positive regulation of interleukin-2 biosynthetic process
GO:0045404	positive regulation of interleukin-4 biosynthetic process
GO:0043017	positive regulation of lymphotoxin A biosynthetic process
GO:0045630	positive regulation of T-helper 2 cell differentiation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0042110	T cell activation
GO:0031295	T cell costimulation
GO:0002224	toll-like receptor signaling pathway
GO:0019048	virus-host interaction

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0005886	plasma membrane

Molecular Function

GO:0015026	coreceptor activity
GO:0005515	protein binding
GO:0004872	receptor activity

CD86 molecule

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function