ATP-binding cassette, sub-family G (WHITE), member 1

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Synonym

ABCG1, WHT1, WHITE1, White protein homolog, ATP-binding cassette sub-family G member 1, ABC8, ATP-binding cassette transporter 8, MGC34313

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:51 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:- retina:118.60 eye:105.80 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:36.40 spleen:37.80 thymus:103.10 bone marrow:98.40 adipose:- bone:25.60 skin:19.20
GeneChip cerebrum:5.21 cerebellum:5.30 brain stem:5.27 corpus callosum/glia:5.46 pineal gland:- peripheral nerve:5.16 spine:4.93 retina:- eye:- artery/aorta:4.66 vein:5.20 lymphnode:5.39 peripheral blood:- spleen:6.08 thymus:5.74 bone marrow:5.24 adipose:5.26 bone:- skin:5.62
CAGE cerebrum:3.41 cerebellum:- brain stem:3.36 corpus callosum/glia:3.82 pineal gland:2.60 peripheral nerve:- spine:3.02 retina:- eye:- artery/aorta:2.86 vein:3.60 lymphnode:3.33 peripheral blood:- spleen:4.26 thymus:3.49 bone marrow:- adipose:3.94 bone:- skin:-
RNA-seq cerebrum:0.35 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:18.20 prostate:22.50 ovary:- testis:21.60 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:25.40     liver/hepato:21.10        lung:44    bladder:- kidney:31.20 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:62.20 breast:37.20 salivary:-
GeneChip uterus:4.94 placenta:5.70 prostate:4.97 ovary:5.06 testis:4.40 heart:5.28 muscle:5.40 esophagus:4.92 stomach:5.18 intestine:4.99 colon:5.44 liver/hepato:4.89 lung:6.26 bladder:- kidney:5.09 pituitary:5.43 thyroid/parathyroid:4.87 adrenal gland:5.81 pancreas:5.19 breast:5.15 salivary:5.39
CAGE uterus:2.58 placenta:2.93 prostate:2.89 ovary:2.75 testis:1.97 heart:3.16 muscle:3.15 esophagus:2.54 stomach:- intestine:3.75 colon:3.06     liver/hepato:2.33    lung:3.85 bladder:3.47 kidney:2.54 pituitary:3.17 thyroid/parathyroid:2.36 adrenal gland:- pancreas:1.59 breast:3.19 salivary:2.97
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:2.11    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.75 adrenal gland:0.38 pancreas:- breast:0.00 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0042987  amyloid precursor protein catabolic process
GO:0033344  cholesterol efflux
GO:0042632  cholesterol homeostasis
GO:0008203  cholesterol metabolic process
GO:0009720  detection of hormone stimulus
GO:0034436  glycoprotein transport
GO:0034375  high-density lipoprotein particle remodeling
GO:0032367  intracellular cholesterol transport
GO:0042157  lipoprotein metabolic process
GO:0034374  low-density lipoprotein particle remodeling
GO:0010887  negative regulation of cholesterol storage
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0033700  phospholipid efflux
GO:0055091  phospholipid homeostasis
GO:0045542  positive regulation of cholesterol biosynthetic process
GO:0010875  positive regulation of cholesterol efflux
GO:0010872  regulation of cholesterol esterification
GO:0006355  regulation of transcription, DNA-dependent
GO:0055099  response to high density lipoprotein stimulus
GO:0033993  response to lipid
GO:0010033  response to organic substance
GO:0043691  reverse cholesterol transport
GO:0055085  transmembrane transport

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0005768  endosome
GO:0009897  external side of plasma membrane
GO:0005794  Golgi apparatus
GO:0000139  Golgi membrane
GO:0005887  integral to plasma membrane
GO:0005739  mitochondrion
GO:0005886  plasma membrane
GO:0055037  recycling endosome

Molecular Function

GO:0043531  ADP binding
GO:0005524  ATP binding
GO:0015485  cholesterol binding
GO:0017127  cholesterol transporter activity
GO:0034437  glycoprotein transporter activity
GO:0005543  phospholipid binding
GO:0005548  phospholipid transporter activity
GO:0046983  protein dimerization activity
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0034041  sterol-transporting ATPase activity
GO:0019534  toxin transporter activity