aldehyde dehydrogenase 1 family, member L1

 jump to detail

Synonym

Fthfd, 1810048F20Rik, Aldehyde dehydrogenase 1 family member L1, 10-FTHFDH, aldehyde dehydrogenase 1 family, member L1, Aldh1l1, 10-formyltetrahydrofolate dehydrogenase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:99 cerebellum:18.40 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:141.90 retina:- eye:7.60 artery/aorta:- vein:- lymphnode:- peripheral blood:71.90 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:15.80
GeneChip cerebrum:8.43 cerebellum:8.66 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.41 spine:8.84 retina:7.21 eye:6.74 artery/aorta:- vein:5.30 lymphnode:7.45 peripheral blood:- spleen:5.47 thymus:- bone marrow:5.57 adipose:9.64 bone:5.12 skin:6.12
CAGE nodata
RNA-seq cerebrum:16.79 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:11.50 testis:29.60 heart:- muscle:177.50 esophagus:- stomach:32.70 intestine:- colon:52.90     liver/hepato:877.90        lung:30.10    bladder:- kidney:266 pituitary:- thyroid/parathyroid:- adrenal gland:848.90 pancreas:18.80 breast:3.30 salivary:108
GeneChip uterus:6.71 placenta:5.17 prostate:7.41 ovary:8.55 testis:7.86 heart:5.86 muscle:7.69 esophagus:- stomach:9.20 intestine:9.49 colon:- liver/hepato:13.39 lung:8.47 bladder:6.27 kidney:11.74 pituitary:6.73 thyroid/parathyroid:- adrenal gland:9.91 pancreas:8.85 breast:8.18 salivary:7.35
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.21 esophagus:- stomach:- intestine:- colon:-     liver/hepato:136.10        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_027406
Gene ID 107747
Unigene ID Mm.30035
Probe set ID 1424400_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030088

Orthologous Gene

Human[1]  NM_012190
Rat[1]  NM_012190

Chromosomal Region

-

Gene Family (Interpro ID)

IPR009081  Acyl carrier protein-like

Link to Pubmed  (Pubmed ID)

7506389
7972060
8889548
10349636
10713084
11042159
11076861
11217851
11488596
12466851
12477932
14681479
15489334
16141072
16141073
16602821
17111379
17309103
17937387
18287559
18614015
18799693
18971422
21267068
21386911
21677750
22627280
22991445
23055941
23223237
23431145
23836537
23895693

Gene Ontology  (GO ID)

Biological Process

GO:0009258  10-formyltetrahydrofolate catabolic process
GO:0009058  biosynthetic process
GO:0008152  metabolic process
GO:0006730  one-carbon metabolic process
GO:0055114  oxidation reduction

Cellular Component

GO:0005737  cytoplasm
GO:0005739  mitochondrion

Molecular Function

GO:0003824  catalytic activity
GO:0016155  formyltetrahydrofolate dehydrogenase activity
GO:0016742  hydroxymethyl-, formyl- and related transferase activity
GO:0008168  methyltransferase activity
GO:0016491  oxidoreductase activity
GO:0016620  oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor