aconitase 2, mitochondrial

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Synonym

Citrate hydro-lyase, D10Wsu183e, Aconitase, Aco2, Aco-2, aconitase 2, mitochondrial, Aco3, Aconitate hydratase, mitochondrial precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:430.70 cerebellum:276.30 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:114.70 spine:283.70 retina:257.20 eye:357.10 artery/aorta:928.30 vein:- lymphnode:97.20 peripheral blood:589.50 spleen:223.80 thymus:148.20 bone marrow:756.50 adipose:- bone:375.70 skin:498.80
GeneChip cerebrum:11.32 cerebellum:11.45 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.72 spine:11.65 retina:9.32 eye:9.26 artery/aorta:- vein:9.41 lymphnode:9.64 peripheral blood:- spleen:9.43 thymus:- bone marrow:9.67 adipose:12.19 bone:10.13 skin:10.43
CAGE cerebrum:4.36 cerebellum:- brain stem:4.63 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.56 retina:- eye:- artery/aorta:5.81 vein:- lymphnode:2.76 peripheral blood:- spleen:2.83 thymus:3.55 bone marrow:- adipose:- bone:3.89 skin:2.99
RNA-seq cerebrum:102.59 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:392.60 placenta:303.80 prostate:92.60 ovary:172.40 testis:162.60 heart:1543.90 muscle:1029.70 esophagus:- stomach:130.90 intestine:258.80 colon:440.60     liver/hepato:153.90        lung:251    bladder:66.20 kidney:1088 pituitary:258.30 thyroid/parathyroid:112.50 adrenal gland:- pancreas:234.60 breast:440.80 salivary:1295.90
GeneChip uterus:10.01 placenta:9.89 prostate:10.41 ovary:10.62 testis:9.74 heart:13.43 muscle:13.08 esophagus:- stomach:11.51 intestine:11.59 colon:- liver/hepato:10.16 lung:10.01 bladder:10.27 kidney:12.23 pituitary:10.52 thyroid/parathyroid:- adrenal gland:12.13 pancreas:9.13 breast:11.73 salivary:10.45
CAGE uterus:3.09 placenta:3.15 prostate:3.36 ovary:3.20 testis:4.17 heart:- muscle:- esophagus:- stomach:3.92 intestine:4.38 colon:4.43     liver/hepato:3.60    lung:3.20 bladder:3.29 kidney:- pituitary:3.20 thyroid/parathyroid:- adrenal gland:3.57 pancreas:2.66 breast:3.91 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:248.91 esophagus:- stomach:- intestine:- colon:-     liver/hepato:32.73        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_080633
Gene ID 11429
Unigene ID Mm.154581
Probe set ID 1436934_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022477

Orthologous Gene

Human [0]  
Rat[1]  NM_024398

Chromosomal Region

-

Gene Family (Interpro ID)

IPR006248  Aconitase, mitochondrial-like
IPR015937  Aconitase-like core

Link to Pubmed  (Pubmed ID)

8288233
8827514
9371744
9811942
9828140
9887327
10349636
10922068
11042159
11076861
11217851
11812828
12466851
12477932
12904583
14610273
14651853
14681479
15317809
15489334
15782199
16141072
16141073
16480904
16602821
16916647
17322295
17615160
17626619
18614015
18799693
19956584
21267068
21278135
24429287

Gene Ontology  (GO ID)

Biological Process

GO:0006101  citrate metabolic process
GO:0006102  isocitrate metabolic process
GO:0008152  metabolic process
GO:0006099  tricarboxylic acid cycle

Cellular Component

GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0051538  3 iron, 4 sulfur cluster binding
GO:0051539  4 iron, 4 sulfur cluster binding
GO:0003994  aconitate hydratase activity
GO:0005506  iron ion binding
GO:0051536  iron-sulfur cluster binding
GO:0016829  lyase activity
GO:0046872  metal ion binding