adrenergic receptor, beta 2

Synonym

Adrb2, Beta-2 adrenergic receptor, adrenergic receptor, beta 2, beta 2-adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Adrb2r, Badm, Gpcr7, beta 2-AR, Adrb-2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:3.72

cerebellum:3.83

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:3.90

spine:3.65

retina:3.71

eye:5.02

artery/aorta:-

vein:5.98

lymphnode:6.56

peripheral blood:-

spleen:6.63

thymus:-

bone marrow:7.45

adipose:4.58

bone:7.32

skin:6.42

CAGE

cerebrum:1.92

cerebellum:-

brain stem:1.77

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.96

retina:-

eye:-

artery/aorta:4.18

vein:-

lymphnode:3.87

peripheral blood:-

spleen:4.30

thymus:3.07

bone marrow:-

adipose:-

bone:4.59

skin:3.40

RNA-seq

cerebrum:0.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:288.20

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.49

placenta:3.82

prostate:4.64

ovary:4.66

testis:3.98

heart:3.93

muscle:7.16

esophagus:-

stomach:3.73

intestine:3.83

colon:-

liver/hepato:4.05

lung:8.28

bladder:4.27

kidney:4.49

pituitary:3.83

thyroid/parathyroid:-

adrenal gland:4.06

pancreas:4.34

breast:5.06

salivary:4.23

CAGE

uterus:3.48

placenta:1.95

prostate:3.50

ovary:2.78

testis:0.75

heart:-

muscle:-

esophagus:-

stomach:2.26

intestine:0.58

colon:1.85

liver/hepato:2.26

lung:5.12

bladder:2.73

kidney:-

pituitary:2.77

thyroid/parathyroid:-

adrenal gland:2.09

pancreas:3.36

breast:3.48

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.20

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0.57

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007420
Gene ID	11555
Unigene ID	Mm.55982
Probe set ID	1437302_at [Mouse430_2]
Ensembl ID	ENSMUSG00000045730

Orthologous Gene

Human[1]	NM_000024
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR000332	Adrenergic receptor, beta 2
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0045453	bone resorption
GO:0050873	brown fat cell differentiation
GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002086	diaphragm contraction
GO:0002024	diet induced thermogenesis
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0031649	heat generation
GO:0016525	negative regulation of angiogenesis
GO:0050728	negative regulation of inflammatory response
GO:0040015	negative regulation of multicellular organism growth
GO:0030279	negative regulation of ossification
GO:0045986	negative regulation of smooth muscle contraction
GO:0043065	positive regulation of apoptosis
GO:0030501	positive regulation of bone mineralization
GO:0008284	positive regulation of cell proliferation
GO:0045823	positive regulation of heart contraction
GO:0043410	positive regulation of MAPKKK cascade
GO:0043268	positive regulation of potassium ion transport
GO:0031398	positive regulation of protein ubiquitination
GO:0048633	positive regulation of skeletal muscle tissue growth
GO:0010765	positive regulation of sodium ion transport
GO:0003059	positive regulation of the force of heart contraction by epinephrine
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045909	positive regulation of vasodilation
GO:0006898	receptor-mediated endocytosis
GO:0051924	regulation of calcium ion transport
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0051930	regulation of sensory perception of pain
GO:0006940	regulation of smooth muscle contraction
GO:0002028	regulation of sodium ion transport
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine
GO:0042312	regulation of vasodilation
GO:0009409	response to cold
GO:0007165	signal transduction
GO:0035249	synaptic transmission, glutamatergic
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0042060	wound healing

Cellular Component

GO:0016324	apical plasma membrane
GO:0030424	axon
GO:0005901	caveola
GO:0032809	cell soma membrane
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043197	dendritic spine
GO:0005768	endosome
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0044424	intracellular part
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043235	receptor complex
GO:0042383	sarcolemma

Molecular Function

GO:0008179	adenylate cyclase binding
GO:0004935	adrenoceptor activity
GO:0004941	beta2-adrenergic receptor activity
GO:0035240	dopamine binding
GO:0008144	drug binding
GO:0051379	epinephrine binding
GO:0001965	G-protein alpha-subunit binding
GO:0004930	G-protein coupled receptor activity
GO:0035255	ionotropic glutamate receptor binding
GO:0051380	norepinephrine binding
GO:0015459	potassium channel regulator activity
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0042803	protein homodimerization activity
GO:0004871	signal transducer activity

adrenergic receptor, beta 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function