cyclin-dependent kinase 5, regulatory subunit 2 (p39)

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Synonym

Nck5ai, Cyclin-dependent kinase 5 activator 2 precursor, P39, p39, Cyclin-dependent kinase 5 regulatory subunit 2, P39I, CDK5 activator 2, Cdk5r2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:15.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.44 cerebellum:6.92 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.64 spine:7.43 retina:6.78 eye:6.39 artery/aorta:- vein:5.69 lymphnode:5.62 peripheral blood:- spleen:5.64 thymus:- bone marrow:5.68 adipose:5.49 bone:5.57 skin:5.22
CAGE cerebrum:4.94 cerebellum:- brain stem:5.20 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.11 retina:- eye:- artery/aorta:0.36 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.26 placenta:5.74 prostate:5.82 ovary:5.04 testis:5.65 heart:5.85 muscle:5.48 esophagus:- stomach:5.95 intestine:5.67 colon:- liver/hepato:5.64 lung:5.13 bladder:5.42 kidney:5.79 pituitary:6.99 thyroid/parathyroid:- adrenal gland:5.98 pancreas:6.53 breast:5.59 salivary:5.72
CAGE uterus:0.17 placenta:0 prostate:1.23 ovary:0 testis:0.45 heart:- muscle:- esophagus:- stomach:1.75 intestine:0.42 colon:0.70     liver/hepato:0    lung:0.17 bladder:1.01 kidney:- pituitary:4.36 thyroid/parathyroid:- adrenal gland:2.18 pancreas:0.84 breast:0 salivary:-
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_009872
Gene ID 12570
Unigene ID Mm.153833
Probe set ID 1450466_at  [Mouse430_2]
Ensembl ID ENSMUSG00000090071

Orthologous Gene

Human[1]  NM_003936
Rat[1]  NM_003936

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
9581970
9655938
10349636
11042159
11076861
11217851
11226314
11239428
11517264
11859196
12223541
12466851
12477932
12496365
12516540
12699769
14985430
15123626
15226823
15908038
16141072
16141073
16600913
16602821
18507738
19017796
21267068
23029270
23645679
24085300

Gene Ontology  (GO ID)

Biological Process

GO:0021549  cerebellum development
GO:0021766  hippocampus development
GO:0021819  layer formation in the cerebral cortex
GO:0001764  neuron migration
GO:0045956  positive regulation of calcium ion-dependent exocytosis
GO:0045860  positive regulation of protein kinase activity
GO:0021722  superior olivary nucleus maturation

Cellular Component

GO:0016533  cyclin-dependent protein kinase 5 holoenzyme complex
GO:0005737  cytoplasm
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0016534  cyclin-dependent protein kinase 5 activator activity
GO:0008092  cytoskeletal protein binding
GO:0008289  lipid binding