cholesterol 25-hydroxylase

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Synonym

cholesterol 25-hydroxylase, Ch25h, AI462618, Cholesterol 25-monooxygenase, Cholesterol 25-hydroxylase, m25OH

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:32.10 eye:- artery/aorta:- vein:- lymphnode:140.40 peripheral blood:- spleen:210.70 thymus:9.90 bone marrow:551.30 adipose:- bone:- skin:31.70
GeneChip cerebrum:4.48 cerebellum:4.69 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.78 spine:4.58 retina:4.70 eye:6.27 artery/aorta:- vein:4.99 lymphnode:6.12 peripheral blood:- spleen:5.60 thymus:- bone marrow:4.53 adipose:4.72 bone:4.34 skin:4.90
CAGE cerebrum:0.30 cerebellum:- brain stem:0.31 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.44 retina:- eye:- artery/aorta:0.54 vein:- lymphnode:2.11 peripheral blood:- spleen:0.86 thymus:0.49 bone marrow:- adipose:- bone:0 skin:0.40
RNA-seq cerebrum:0.46 cerebellum:0.46 brain stem:0.46 corpus callosum/glia:0.46 pineal gland:0.46 peripheral nerve:0.46 spine:0.46 retina:0.46 eye:0.46 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:18.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:19.60 salivary:-
GeneChip uterus:4.69 placenta:4.51 prostate:4.88 ovary:4.97 testis:4.45 heart:4.75 muscle:4.78 esophagus:- stomach:4.82 intestine:4.69 colon:- liver/hepato:4.50 lung:5.34 bladder:4.94 kidney:4.85 pituitary:4.51 thyroid/parathyroid:- adrenal gland:4.41 pancreas:4.83 breast:4.75 salivary:5.23
CAGE uterus:1.16 placenta:0.70 prostate:0 ovary:1.05 testis:0 heart:- muscle:- esophagus:- stomach:1.57 intestine:0.72 colon:1.03     liver/hepato:0    lung:1.85 bladder:0.57 kidney:- pituitary:0.29 thyroid/parathyroid:- adrenal gland:0.91 pancreas:0.84 breast:0.43 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_009890
Gene ID 12642
Unigene ID Mm.30824
Probe set ID 1449227_at  [Mouse430_2]
Ensembl ID ENSMUSG00000050370

Orthologous Gene

Human[1]  NM_003956
Rat[1]  NM_001025415

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9852097
10349636
11042159
11076861
11217851
12466851
12477932
12543708
14681479
15489334
16141072
16141073
16602821
19502589
19805370
21263022
21796212
22999953
23239817
23273844
23502855
23558016
23682316

Gene Ontology  (GO ID)

Biological Process

GO:0008203  cholesterol metabolic process
GO:0006633  fatty acid biosynthetic process
GO:0006629  lipid metabolic process
GO:0055114  oxidation reduction
GO:0006694  steroid biosynthetic process
GO:0008202  steroid metabolic process
GO:0016126  sterol biosynthetic process

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0016020  membrane

Molecular Function

GO:0001567  cholesterol 25-hydroxylase activity
GO:0005506  iron ion binding
GO:0046872  metal ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0008395  steroid hydroxylase activity