double C2, beta

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Synonym

Doc2-beta, Double C2-like domain-containing protein beta, double C2, beta, Doc2b

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:76.40 spine:- retina:64.30 eye:91.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:26.30 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.05 cerebellum:6.39 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.11 spine:4.72 retina:5.08 eye:5.19 artery/aorta:- vein:4.34 lymphnode:4.22 peripheral blood:- spleen:4.10 thymus:- bone marrow:4.22 adipose:4.17 bone:4.14 skin:4.26
CAGE cerebrum:4.76 cerebellum:- brain stem:3.17 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.51 retina:- eye:- artery/aorta:1.20 vein:- lymphnode:1.12 peripheral blood:- spleen:0.16 thymus:0.95 bone marrow:- adipose:- bone:0 skin:0.84
RNA-seq cerebrum:7.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:11.50 testis:29.60 heart:18.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.30 placenta:4.55 prostate:6.81 ovary:5.29 testis:4.77 heart:4.56 muscle:4.23 esophagus:- stomach:4.24 intestine:4.23 colon:- liver/hepato:4.31 lung:4.24 bladder:4.15 kidney:4.35 pituitary:5.23 thyroid/parathyroid:- adrenal gland:5.26 pancreas:4.71 breast:4.40 salivary:4.70
CAGE uterus:1.90 placenta:1.74 prostate:3.18 ovary:3.75 testis:1.89 heart:- muscle:- esophagus:- stomach:0 intestine:0.95 colon:0.41     liver/hepato:0    lung:1.46 bladder:1.41 kidney:- pituitary:3.05 thyroid/parathyroid:- adrenal gland:3.92 pancreas:1.61 breast:2.52 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.32 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007873
Gene ID 13447
Unigene ID Mm.5137
Probe set ID 1420666_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020848

Orthologous Gene

Human[1]  NM_003585
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000008  C2 calcium-dependent membrane targeting
IPR008973  C2 calcium/lipid-binding domain, CaLB
IPR018029  C2 membrane targeting protein

Link to Pubmed  (Pubmed ID)

8902635
12466851
12477932
15145078
15489334
15935055
16284245
16515538
16602821
17548353
18541526
18596155
19033398
19410553
20150444
21267068
21521611
21677750
22698913
23341629
24133251

Gene Ontology  (GO ID)

Biological Process

GO:0048791  calcium ion-dependent exocytosis of neurotransmitter
GO:0045956  positive regulation of calcium ion-dependent exocytosis
GO:0032024  positive regulation of insulin secretion
GO:0031340  positive regulation of vesicle fusion
GO:0008104  protein localization
GO:0006810  transport

Cellular Component

GO:0005737  cytoplasm
GO:0016020  membrane
GO:0015630  microtubule cytoskeleton
GO:0005886  plasma membrane
GO:0031201  SNARE complex
GO:0008021  synaptic vesicle

Molecular Function

GO:0005544  calcium-dependent phospholipid binding
GO:0005515  protein binding
GO:0019905  syntaxin binding
GO:0005215  transporter activity