dishevelled, dsh homolog 1 (Drosophila)

Synonym

Dishevelled-1, Dvl, dishevelled, dsh homolog 1 (Drosophila), Dvl1, DSH homolog 1, Segment polarity protein dishevelled homolog DVL-1, mKIAA4029, KIAA4029

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:10.18

cerebellum:10.55

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:9.91

spine:9.43

retina:10.21

eye:10.13

artery/aorta:-

vein:9.82

lymphnode:9.08

peripheral blood:-

spleen:9.26

thymus:-

bone marrow:9.20

adipose:10.27

bone:9.90

skin:11.07

CAGE

cerebrum:3.71

cerebellum:-

brain stem:3.54

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.48

retina:-

eye:-

artery/aorta:2.88

vein:-

lymphnode:1.98

peripheral blood:-

spleen:2.86

thymus:2.49

bone marrow:-

adipose:-

bone:3.41

skin:3.37

RNA-seq

cerebrum:15.71

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:9.61

placenta:9.95

prostate:10.43

ovary:9.48

testis:10.08

heart:9.55

muscle:11.40

esophagus:-

stomach:9.57

intestine:9.41

colon:-

liver/hepato:9.84

lung:9.73

bladder:9.41

kidney:9.89

pituitary:10.04

thyroid/parathyroid:-

adrenal gland:10.76

pancreas:11.22

breast:10.39

salivary:10.47

CAGE

uterus:3.13

placenta:3.13

prostate:3.48

ovary:3.25

testis:4.88

heart:-

muscle:-

esophagus:-

stomach:3.64

intestine:3.69

colon:3.59

liver/hepato:3.98

lung:3.17

bladder:3.15

kidney:-

pituitary:3.36

thyroid/parathyroid:-

adrenal gland:3.21

pancreas:3.99

breast:3.31

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:15.85

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:11.16

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010091
Gene ID	13542
Unigene ID	Mm.340014
Probe set ID	1437301_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000029071

Orthologous Gene

Human[1]	NM_004421
Rat[1]	NM_031820

Chromosomal Region

Gene Family (Interpro ID)

IPR000591	DEP domain
IPR015506	Dishevelled related protein
IPR008340	Dishevelled-1 protein
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0048675	axon extension
GO:0007411	axon guidance
GO:0007409	axonogenesis
GO:0090103	cochlea morphogenesis
GO:0048668	collateral sprouting
GO:0022007	convergent extension involved in neural plate elongation
GO:0060029	convergent extension involved in organogenesis
GO:0031122	cytoplasmic microtubule organization
GO:0048813	dendrite morphogenesis
GO:0007275	multicellular organismal development
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0032091	negative regulation of protein binding
GO:0006469	negative regulation of protein kinase activity
GO:0007528	neuromuscular junction development
GO:0007269	neurotransmitter secretion
GO:0090179	planar cell polarity pathway involved in neural tube closure
GO:0010976	positive regulation of neuron projection development
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0060134	prepulse inhibition
GO:0034504	protein localization in nucleus
GO:0043113	receptor clustering
GO:0001505	regulation of neurotransmitter levels
GO:0001932	regulation of protein amino acid phosphorylation
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering
GO:0035176	social behavior
GO:0050808	synapse organization
GO:0006366	transcription from RNA polymerase II promoter
GO:0016055	Wnt receptor signaling pathway
GO:0060070	Wnt receptor signaling pathway through beta-catenin
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway

Cellular Component

GO:0030424	axon
GO:0005938	cell cortex
GO:0043025	cell soma
GO:0030136	clathrin-coated vesicle
GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0031410	cytoplasmic vesicle
GO:0030425	dendrite
GO:0030426	growth cone
GO:0005622	intracellular
GO:0016328	lateral plasma membrane
GO:0016020	membrane
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton
GO:0005886	plasma membrane
GO:0045202	synapse

Molecular Function

GO:0019899	enzyme binding
GO:0005109	frizzled binding
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0048365	Rac GTPase binding
GO:0004871	signal transducer activity

dishevelled, dsh homolog 1 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function