eukaryotic translation initiation factor 4A1

 jump to detail

Synonym

Eif4a, ATP-dependent RNA helicase eIF4A-1, eIF-4A-I, Eif4, Eukaryotic initiation factor 4A-I, eukaryotic translation initiation factor 4A1, initiation factor eIF-4A long form, Ddx2a, BM-010, eIF4A-I, Eif4a1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:276.10 cerebellum:239.50 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:1222.90 spine:756.60 retina:128.60 eye:190 artery/aorta:- vein:- lymphnode:75.60 peripheral blood:86.30 spleen:158 thymus:207.50 bone marrow:256.40 adipose:- bone:350.70 skin:451.30
GeneChip cerebrum:11.28 cerebellum:10.92 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11 spine:10.46 retina:7.59 eye:7.54 artery/aorta:- vein:12.39 lymphnode:12.38 peripheral blood:- spleen:12.07 thymus:- bone marrow:12.39 adipose:11.56 bone:12.24 skin:11.99
CAGE cerebrum:3.03 cerebellum:- brain stem:3.00 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.85 retina:- eye:- artery/aorta:2.14 vein:- lymphnode:2.26 peripheral blood:- spleen:2.66 thymus:2.66 bone marrow:- adipose:- bone:2.72 skin:2.50
RNA-seq cerebrum:28.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1875.80 placenta:428 prostate:- ovary:723.90 testis:133 heart:520.80 muscle:248.60 esophagus:- stomach:490.90 intestine:147.90 colon:282     liver/hepato:135.80        lung:321.30    bladder:330.90 kidney:411 pituitary:477.90 thyroid/parathyroid:- adrenal gland:- pancreas:281.50 breast:346.10 salivary:54
GeneChip uterus:12.66 placenta:12.16 prostate:11.80 ovary:12.59 testis:10.48 heart:10.40 muscle:10.43 esophagus:- stomach:12.01 intestine:11.96 colon:- liver/hepato:11.73 lung:11.51 bladder:11.83 kidney:11.17 pituitary:11.48 thyroid/parathyroid:- adrenal gland:12.06 pancreas:11.30 breast:12 salivary:10.95
CAGE uterus:2.79 placenta:3.09 prostate:2.17 ovary:2.54 testis:4.48 heart:- muscle:- esophagus:- stomach:2.16 intestine:2.27 colon:2.32     liver/hepato:2.13    lung:2.21 bladder:2.17 kidney:- pituitary:3.02 thyroid/parathyroid:- adrenal gland:2.41 pancreas:2.83 breast:2.65 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:23.90 esophagus:- stomach:- intestine:- colon:-     liver/hepato:47.87        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_144958
Gene ID 13681
Unigene ID Mm.371557
Probe set ID 1427058_at  [Mouse430_2]
Ensembl ID ENSMUSG00000059796

Orthologous Gene

Human[2]  NM_001204510, NM_001416
Rat[1]  NM_199372, NM_001416

Chromosomal Region

11B3  [69,480,438  -  69,485,925]

Gene Family (Interpro ID)

IPR014001  DEAD-like helicase, N-terminal
IPR014021  Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed  (Pubmed ID)

1378397
3046931
3215517
3840589
8144024
8226859
8439732
8889548
9015395
9507200
10349636
10524236
10922068
11042159
11076861
11217851
12466851
12477932
12482958
12904583
14610273
15177550
15489334
15782199
16030146
16033648
16141072
16141073
16289705
16541103
17060447
17130132
18799693
19153607
21266579
21454508
21677750
21930783
22354994
22673621
23649778
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0006412  translation
GO:0006413  translational initiation

Molecular Function

GO:0005524  ATP binding
GO:0008026  ATP-dependent helicase activity
GO:0004386  helicase activity
GO:0016787  hydrolase activity
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0003723  RNA binding
GO:0003743  translation initiation factor activity