growth hormone receptor

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Synonym

GHBP, AA986417, Growth hormone receptor precursor, GHR/BP, growth hormone receptor, Ghr, Somatotropin receptor, GH receptor

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.09 cerebellum:6.97 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.08 spine:6.04 retina:5.70 eye:6.08 artery/aorta:- vein:9.04 lymphnode:7.07 peripheral blood:- spleen:5.79 thymus:- bone marrow:5.97 adipose:10.54 bone:6.23 skin:7.21
CAGE cerebrum:2.08 cerebellum:- brain stem:2.68 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.96 retina:- eye:- artery/aorta:5.75 vein:- lymphnode:2.90 peripheral blood:- spleen:1.60 thymus:2.29 bone marrow:- adipose:- bone:3.32 skin:4.94
RNA-seq cerebrum:4.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:7.05 placenta:8.24 prostate:6.70 ovary:8.31 testis:5.48 heart:8.94 muscle:9.77 esophagus:- stomach:7.43 intestine:6.63 colon:- liver/hepato:10.96 lung:8.04 bladder:7.19 kidney:11.20 pituitary:6.13 thyroid/parathyroid:- adrenal gland:7.55 pancreas:7.62 breast:9.55 salivary:6.62
CAGE uterus:3.56 placenta:3.59 prostate:2.45 ovary:4.52 testis:1.60 heart:- muscle:- esophagus:- stomach:4.20 intestine:2.83 colon:3.23     liver/hepato:6.26    lung:4.45 bladder:4.14 kidney:- pituitary:2.53 thyroid/parathyroid:- adrenal gland:3.96 pancreas:5.28 breast:4.97 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:12.60 esophagus:- stomach:- intestine:- colon:-     liver/hepato:44.44        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_010284
Gene ID 14600
Unigene ID Mm.39860
Probe set ID 1451871_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000055737

Orthologous Gene

Human[2]  NM_000163, NM_001242399, NM_001242400, NM_001242401, NM_001242402, NM_001242403, NM_001242404, NM_001242405, NM_001242406, NM_001242460, NM_001242461, NM_001242462
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0042977  activation of JAK2 kinase activity
GO:0042976  activation of Janus kinase activity
GO:0000187  activation of MAPK activity
GO:0000255  allantoin metabolic process
GO:0032870  cellular response to hormone stimulus
GO:0006101  citrate metabolic process
GO:0006600  creatine metabolic process
GO:0046449  creatinine metabolic process
GO:0019221  cytokine-mediated signaling pathway
GO:0006897  endocytosis
GO:0006631  fatty acid metabolic process
GO:0060396  growth hormone receptor signaling pathway
GO:0009755  hormone-mediated signaling pathway
GO:0048009  insulin-like growth factor receptor signaling pathway
GO:0006549  isoleucine metabolic process
GO:0007259  JAK-STAT cascade
GO:0044236  multicellular organismal metabolic process
GO:0006107  oxaloacetate metabolic process
GO:0046427  positive regulation of JAK-STAT cascade
GO:0040018  positive regulation of multicellular organism growth
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0040014  regulation of multicellular organism growth
GO:0032355  response to estradiol stimulus
GO:0006105  succinate metabolic process
GO:0019530  taurine metabolic process
GO:0006573  valine metabolic process

Cellular Component

GO:0043025  cell soma
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0019898  extrinsic to membrane
GO:0070195  growth hormone receptor complex
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0004896  cytokine receptor activity
GO:0019838  growth factor binding
GO:0004903  growth hormone receptor activity
GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0019903  protein phosphatase binding
GO:0042169  SH2 domain binding