isocitrate dehydrogenase 3 (NAD+) beta

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Synonym

Idh3b, C78231, isocitrate dehydrogenase 3 (NAD+) beta

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:64.30 eye:7.60 artery/aorta:- vein:- lymphnode:21.60 peripheral blood:- spleen:13.20 thymus:29.60 bone marrow:- adipose:- bone:- skin:39.60
GeneChip cerebrum:11.51 cerebellum:11.87 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.27 spine:11.72 retina:10.08 eye:10.17 artery/aorta:- vein:10.21 lymphnode:10.73 peripheral blood:- spleen:10.52 thymus:- bone marrow:9.95 adipose:12.10 bone:10.07 skin:10.71
CAGE cerebrum:5.72 cerebellum:- brain stem:5.97 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.73 retina:- eye:- artery/aorta:7.09 vein:- lymphnode:4.84 peripheral blood:- spleen:4.63 thymus:4.79 bone marrow:- adipose:- bone:5.39 skin:5.21
RNA-seq cerebrum:50.51 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:- prostate:- ovary:91.90 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:16.30 salivary:-
GeneChip uterus:10.98 placenta:9.84 prostate:10.73 ovary:11.01 testis:10.12 heart:12.92 muscle:12.67 esophagus:- stomach:11.54 intestine:11.45 colon:- liver/hepato:11.47 lung:10.40 bladder:10.82 kidney:12.08 pituitary:10.11 thyroid/parathyroid:- adrenal gland:11.97 pancreas:10.17 breast:11.65 salivary:10.83
CAGE uterus:5.07 placenta:4.60 prostate:4.90 ovary:4.88 testis:5.71 heart:- muscle:- esophagus:- stomach:5.88 intestine:5.59 colon:5.58     liver/hepato:5.93    lung:4.72 bladder:5.16 kidney:- pituitary:4.64 thyroid/parathyroid:- adrenal gland:5.21 pancreas:4.90 breast:5.04 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:125.82 esophagus:- stomach:- intestine:- colon:-     liver/hepato:36.85        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_130884
Gene ID 170718
Unigene ID Mm.295906
Probe set ID 1418886_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000027406

Orthologous Gene

Human[8]  NM_006899, NM_174855, NM_174856
Rat[1]  NM_053581, NM_174855, NM_174856

Chromosomal Region

-

Gene Family (Interpro ID)

IPR004434  Isocitrate dehydrogenase NAD-dependent, mitochondrial
IPR001804  Isocitrate/isopropylmalate dehydrogenase

Link to Pubmed  (Pubmed ID)

8889548
10349636
10725249
11042159
11076861
11217851
12466851
12477932
12904583
14651853
14681479
15782199
16141072
16141073
16959763
17626619
18614015
21677750
21725061
22083510

Gene Ontology  (GO ID)

Biological Process

GO:0006103  2-oxoglutarate metabolic process
GO:0006102  isocitrate metabolic process
GO:0006734  NADH metabolic process
GO:0055114  oxidation reduction
GO:0006099  tricarboxylic acid cycle

Cellular Component

GO:0005739  mitochondrion

Molecular Function

GO:0004449  isocitrate dehydrogenase (NAD+) activity
GO:0016491  oxidoreductase activity