malate dehydrogenase 1, NAD (soluble)

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Synonym

D17921, Mor-2, MDH-s, malate dehydrogenase 1, NAD (soluble), Mor2, Cytosolic malate dehydrogenase, Mdh1, B230377B03Rik, MDHA, Malate dehydrogenase, cytoplasmic

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:373.40 cerebellum:478.90 brain stem:349.60 corpus callosum/glia:- pineal gland:1289 peripheral nerve:133.80 spine:141.90 retina:385.70 eye:425.50 artery/aorta:- vein:- lymphnode:108 peripheral blood:258.80 spleen:92.20 thymus:138.30 bone marrow:205.10 adipose:- bone:125.20 skin:261.30
GeneChip cerebrum:12.09 cerebellum:12.29 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:12.14 spine:12.17 retina:11.29 eye:11.30 artery/aorta:- vein:10.79 lymphnode:11.04 peripheral blood:- spleen:10.69 thymus:- bone marrow:10.76 adipose:11.95 bone:11.16 skin:11.38
CAGE cerebrum:6.43 cerebellum:- brain stem:7.00 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:6.77 retina:- eye:- artery/aorta:6.47 vein:- lymphnode:4.74 peripheral blood:- spleen:4.69 thymus:5.30 bone marrow:- adipose:- bone:5.33 skin:5.03
RNA-seq cerebrum:182.11 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:305.40 placenta:248.50 prostate:1111.80 ovary:149.40 testis:96.10 heart:2102 muscle:1171.80 esophagus:- stomach:392.70 intestine:110.90 colon:282     liver/hepato:778.30        lung:200.80    bladder:198.50 kidney:1321.70 pituitary:129.20 thyroid/parathyroid:112.50 adrenal gland:- pancreas:609.80 breast:362.40 salivary:324
GeneChip uterus:10.82 placenta:10.73 prostate:11.56 ovary:11.42 testis:8.24 heart:12.40 muscle:12 esophagus:- stomach:11.85 intestine:11.76 colon:- liver/hepato:12.03 lung:11.03 bladder:11.22 kidney:12.32 pituitary:11.69 thyroid/parathyroid:- adrenal gland:12 pancreas:11.04 breast:11.79 salivary:11.43
CAGE uterus:5.01 placenta:4.79 prostate:5.99 ovary:5.26 testis:3.92 heart:- muscle:- esophagus:- stomach:6.22 intestine:6.50 colon:6.90     liver/hepato:6.89    lung:4.95 bladder:5.27 kidney:- pituitary:5.71 thyroid/parathyroid:- adrenal gland:5.73 pancreas:5.29 breast:6.15 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:110.23 esophagus:- stomach:- intestine:- colon:-     liver/hepato:100.56        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_008618
Gene ID 17449
Unigene ID Mm.212703
Probe set ID 1454925_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020321

Orthologous Gene

Human[1]  NM_001199111, NM_001199112, NM_005917
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001557  L-lactate/malate dehydrogenase
IPR001236  Lactate/malate dehydrogenase
IPR011274  Malate dehydrogenase, NAD-dependent, cytosolic
IPR010945  Malate dehydrogenase, NAD/NADP

Link to Pubmed  (Pubmed ID)

3172222
3312200
3796661
5496232
7698769
8786100
8833262
8863742
8889548
9162260
9507200
9799840
10349636
10886019
10922068
11042159
11076861
11217851
12174196
12466851
12477932
14681479
15489334
16141072
16141073
16962111
17626619
18614015
19229245
21278135
21677750
22693256

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0044262  cellular carbohydrate metabolic process
GO:0006108  malate metabolic process
GO:0019674  NAD metabolic process
GO:0006734  NADH metabolic process
GO:0006107  oxaloacetate metabolic process
GO:0055114  oxidation reduction
GO:0006099  tricarboxylic acid cycle

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion

Molecular Function

GO:0003824  catalytic activity
GO:0030060  L-malate dehydrogenase activity
GO:0016615  malate dehydrogenase activity
GO:0051287  NAD or NADH binding
GO:0016491  oxidoreductase activity
GO:0016616  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor