septin 2

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Synonym

Protein NEDD5, Sept2, Septin-2, mKIAA0158, Nedd-5, Nedd5, septin 2, AW208991

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:147.60 cerebellum:55.30 brain stem:63.60 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:515.90 spine:331 retina:64.30 eye:91.20 artery/aorta:168.80 vein:- lymphnode:248.40 peripheral blood:28.80 spleen:223.80 thymus:148.20 bone marrow:307.70 adipose:638.20 bone:250.50 skin:213.80
GeneChip cerebrum:8.61 cerebellum:8.61 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.05 spine:9.23 retina:8.26 eye:9.30 artery/aorta:- vein:11.17 lymphnode:9.83 peripheral blood:- spleen:9.62 thymus:- bone marrow:9.71 adipose:10.01 bone:10.21 skin:10.14
CAGE cerebrum:3.94 cerebellum:- brain stem:4.05 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.29 retina:- eye:- artery/aorta:4.73 vein:- lymphnode:4.83 peripheral blood:- spleen:4.20 thymus:4.22 bone marrow:- adipose:- bone:4.40 skin:4.28
RNA-seq cerebrum:2.81 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:510.90 prostate:154.40 ovary:68.90 testis:125.60 heart:427.80 muscle:106.50 esophagus:- stomach:261.80 intestine:813.40 colon:70.50     liver/hepato:27.20        lung:200.80    bladder:198.50 kidney:72.50 pituitary:1304.60 thyroid/parathyroid:449.90 adrenal gland:- pancreas:431.60 breast:189.40 salivary:-
GeneChip uterus:10.13 placenta:10.63 prostate:10.07 ovary:10.55 testis:9.63 heart:10.02 muscle:9.45 esophagus:- stomach:9.47 intestine:9.61 colon:- liver/hepato:9.63 lung:10.79 bladder:10.39 kidney:9.19 pituitary:10.50 thyroid/parathyroid:- adrenal gland:10.14 pancreas:8.95 breast:10.10 salivary:9.27
CAGE uterus:4.86 placenta:5.23 prostate:4.56 ovary:4.88 testis:5.19 heart:- muscle:- esophagus:- stomach:4.27 intestine:4.14 colon:4.21     liver/hepato:4.03    lung:5.09 bladder:4.85 kidney:- pituitary:4.80 thyroid/parathyroid:- adrenal gland:4.61 pancreas:3.94 breast:4.73 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.75 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.70        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001159718
Gene ID 18000
Unigene ID Mm.428652
Probe set ID 1423472_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026276

Orthologous Gene

Human[8]  NM_001008491, NM_001008492, NM_004404, NM_006155
Rat [0]  

Chromosomal Region

1D  [95,375,541  -  95,406,837]

Gene Family (Interpro ID)

IPR000038  Cell division/GTP binding protein
IPR016491  Septin
IPR008113  Septin 2

Link to Pubmed  (Pubmed ID)

1378265
8889548
9203580
9205941
9811347
10349636
11042159
11064363
11076861
11217851
11584266
11739749
12466851
12477932
12479805
12520002
12904583
14610273
14621295
14723703
15703188
15782199
16059910
16141072
16141073
16371649
16452087
16602821
16739252
17024187
17967808
18799693
19156860
19723774
19805342
20372094
20558667
21267068
21677750
21725061
22083510
22179047
22575789
24302887
24344182

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0051301  cell division
GO:0042384  cilium assembly
GO:0000910  cytokinesis
GO:0006184  GTP catabolic process
GO:0007067  mitosis
GO:0031175  neuron projection development
GO:0051258  protein polymerization
GO:0050790  regulation of catalytic activity
GO:0002036  regulation of L-glutamate transport
GO:0032880  regulation of protein localization
GO:0007224  smoothened signaling pathway

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005826  actomyosin contractile ring
GO:0005938  cell cortex
GO:0042995  cell projection
GO:0009986  cell surface
GO:0005694  chromosome
GO:0000775  chromosome, centromeric region
GO:0060170  cilium membrane
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0000145  exocyst
GO:0000776  kinetochore
GO:0016020  membrane
GO:0015630  microtubule cytoskeleton
GO:0030496  midbody
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0031105  septin complex
GO:0005876  spindle microtubule
GO:0045202  synapse

Molecular Function

GO:0030234  enzyme regulator activity
GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0042802  identical protein binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0032947  protein complex scaffold