purinergic receptor P2X, ligand-gated ion channel, 6

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Synonym

Purinergic receptor P2X-like 1, P2xm, MGC141601, purinergic receptor P2X-like 1, orphan receptor, P2rx6, P2X purinoceptor 6, P2X6, P2XM, P2rxl1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:47.30 retina:- eye:7.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.25 cerebellum:5.31 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.07 spine:5.87 retina:5.23 eye:5.73 artery/aorta:- vein:5.27 lymphnode:5.17 peripheral blood:- spleen:5.46 thymus:- bone marrow:5.55 adipose:5.70 bone:5.36 skin:5.22
CAGE cerebrum:0.68 cerebellum:- brain stem:1.59 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.85 retina:- eye:- artery/aorta:1.83 vein:- lymphnode:0.23 peripheral blood:- spleen:0.16 thymus:0.27 bone marrow:- adipose:- bone:1.84 skin:1.38
RNA-seq cerebrum:1.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:155 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.94 placenta:5.51 prostate:5.84 ovary:5.43 testis:5.25 heart:5.26 muscle:6.35 esophagus:- stomach:5.45 intestine:5.24 colon:- liver/hepato:5.20 lung:5.51 bladder:5.34 kidney:5.28 pituitary:5.56 thyroid/parathyroid:- adrenal gland:5.19 pancreas:6.36 breast:5.45 salivary:5.75
CAGE uterus:2.24 placenta:0.29 prostate:1.56 ovary:2.00 testis:0.45 heart:- muscle:- esophagus:- stomach:0 intestine:0.23 colon:0.82     liver/hepato:0.26    lung:1.38 bladder:1.14 kidney:- pituitary:1.81 thyroid/parathyroid:- adrenal gland:1.02 pancreas:0.84 breast:0.88 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.23 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001159561
Gene ID 18440
Unigene ID Mm.8032
Probe set ID 1450327_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022758

Orthologous Gene

Human[4]  NM_001159554, NM_005446
Rat [0]  

Chromosomal Region

16A3  [17,561,978  -  17,577,893]

Gene Family (Interpro ID)

IPR001429  P2X purinoreceptor
IPR003049  P2X6 purinoceptor

Link to Pubmed  (Pubmed ID)

8889548
9852680
10349636
11042159
11076861
11217851
12466851
12477932
16141072
16141073
16985003
17605080
18657557
19076210
19442872
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0006812  cation transport
GO:0034220  ion transmembrane transport
GO:0006811  ion transport
GO:0051291  protein heterooligomerization
GO:0051260  protein homooligomerization
GO:0006810  transport

Cellular Component

GO:0030054  cell junction
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0043197  dendritic spine
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0014069  postsynaptic density

Molecular Function

GO:0005524  ATP binding
GO:0004931  ATP-gated cation channel activity
GO:0042802  identical protein binding
GO:0005216  ion channel activity
GO:0001614  purinergic nucleotide receptor activity