protein phosphatase 3, catalytic subunit, alpha isoform

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Synonym

Caln, CN, 2900074D19Rik, PP2B alpha 1, CnA, AW413465, Calna, AI841391, MGC106804, PP2BA alpha, Ppp3ca

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:295.20

cerebellum:147.40

brain stem:95.30

corpus callosum/glia:-

pineal gland:-

peripheral nerve:191.10

spine:283.70

retina:225

eye:106.40

artery/aorta:-

vein:-

lymphnode:21.60

peripheral blood:230

spleen:210.70

thymus:39.50

bone marrow:89.80

adipose:-

bone:100.20

skin:95

GeneChip

cerebrum:12.19

cerebellum:11.46

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:11.47

spine:11.09

retina:9.10

eye:9.07

artery/aorta:-

vein:8.58

lymphnode:9.28

peripheral blood:-

spleen:9.29

thymus:-

bone marrow:8.93

adipose:8.77

bone:9.32

skin:9.89

CAGE

cerebrum:5.91

cerebellum:-

brain stem:4.79

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.98

retina:-

eye:-

artery/aorta:3.75

vein:-

lymphnode:4.44

peripheral blood:-

spleen:3.71

thymus:2.41

bone marrow:-

adipose:-

bone:4.18

skin:4.22

RNA-seq

cerebrum:56.06

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:174.50

placenta:179.50

prostate:185.30

ovary:34.50

testis:155.20

heart:18.60

muscle:-

esophagus:-

stomach:392.70

intestine:184.90

colon:70.50

liver/hepato:45.30

lung:120.50

bladder:-

kidney:80.60

pituitary:103.30

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:65.70

breast:140.40

salivary:54

GeneChip

uterus:8.87

placenta:8.36

prostate:9.73

ovary:8.95

testis:9.49

heart:8.48

muscle:10.77

esophagus:-

stomach:8.73

intestine:8.39

colon:-

liver/hepato:8.02

lung:9.78

bladder:9.28

kidney:7.77

pituitary:9.75

thyroid/parathyroid:-

adrenal gland:9.33

pancreas:8.85

breast:9.47

salivary:8.97

CAGE

uterus:3.78

placenta:3.36

prostate:4.74

ovary:3.69

testis:5.76

heart:-

muscle:-

esophagus:-

stomach:3.94

intestine:3.13

colon:3.72

liver/hepato:3.29

lung:4.60

bladder:4.29

kidney:-

pituitary:4.08

thyroid/parathyroid:-

adrenal gland:3.18

pancreas:4.37

breast:3.48

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:14.27

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:3.80

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008913
Gene ID	19055
Unigene ID	Mm.331389
Probe set ID	1438478_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028161

Orthologous Gene

Human[9]	NM_000944, NM_001130691, NM_001130692
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR004843	Metallophosphoesterase
IPR006186	Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

Gene Ontology (GO ID)

Biological Process

GO:0033173	calcineurin-NFAT signaling pathway
GO:0006816	calcium ion transport
GO:0019722	calcium-mediated signaling
GO:0071333	cellular response to glucose stimulus
GO:0016311	dephosphorylation
GO:0000082	G1/S transition of mitotic cell cycle
GO:0033555	multicellular organismal response to stress
GO:0046676	negative regulation of insulin secretion
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006470	protein amino acid dephosphorylation
GO:0006606	protein import into nucleus
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0050804	regulation of synaptic transmission
GO:0051592	response to calcium ion
GO:0048741	skeletal muscle fiber development
GO:0014883	transition between fast and slow fiber

Cellular Component

GO:0005955	calcineurin complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005622	intracellular
GO:0016020	membrane
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0030018	Z disc

Molecular Function

GO:0004723	calcium-dependent protein serine/threonine phosphatase activity
GO:0005516	calmodulin binding
GO:0033192	calmodulin-dependent protein phosphatase activity
GO:0008144	drug binding
GO:0019899	enzyme binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding
GO:0004721	phosphoprotein phosphatase activity
GO:0005515	protein binding
GO:0046983	protein dimerization activity
GO:0046982	protein heterodimerization activity
GO:0004722	protein serine/threonine phosphatase activity

protein phosphatase 3, catalytic subunit, alpha isoform

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function