legumain

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Synonym

legumain, Prsc1, Asparaginyl endopeptidase, AEP, Protease, cysteine 1, Legumain precursor, preprolegumain, AI746452, AU022324, Lgmn

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:36.50 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:257.80 peripheral nerve:19.10 spine:- retina:64.30 eye:76 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:14.40 spleen:13.20 thymus:9.90 bone marrow:51.30 adipose:- bone:62.60 skin:23.80
GeneChip cerebrum:9.15 cerebellum:9.17 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.97 spine:10.34 retina:8.22 eye:7.65 artery/aorta:- vein:9.49 lymphnode:10.80 peripheral blood:- spleen:10.04 thymus:- bone marrow:8.85 adipose:8.76 bone:8.94 skin:7.27
CAGE cerebrum:4.39 cerebellum:- brain stem:5.11 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.38 retina:- eye:- artery/aorta:4.28 vein:- lymphnode:5.29 peripheral blood:- spleen:4.57 thymus:3.54 bone marrow:- adipose:- bone:4.47 skin:4.17
RNA-seq cerebrum:32.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:138.10 prostate:30.90 ovary:11.50 testis:- heart:18.60 muscle:35.50 esophagus:- stomach:- intestine:37 colon:176.20     liver/hepato:63.40        lung:140.60    bladder:- kidney:386.90 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:143.70 salivary:108
GeneChip uterus:9.96 placenta:12.06 prostate:7.84 ovary:10.64 testis:8.34 heart:8.42 muscle:8.19 esophagus:- stomach:8.41 intestine:8.81 colon:- liver/hepato:8.68 lung:9.69 bladder:8.88 kidney:11.86 pituitary:8.95 thyroid/parathyroid:- adrenal gland:8.91 pancreas:5.61 breast:8.62 salivary:7.54
CAGE uterus:4.25 placenta:5.89 prostate:3.00 ovary:5.06 testis:3.08 heart:- muscle:- esophagus:- stomach:4.13 intestine:4.39 colon:4.23     liver/hepato:4.37    lung:4.55 bladder:4.35 kidney:- pituitary:4.18 thyroid/parathyroid:- adrenal gland:4.89 pancreas:2.83 breast:3.74 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:5.26 esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.29        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_011175
Gene ID 19141
Unigene ID Mm.17185
Probe set ID 1448883_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021190

Orthologous Gene

Human[2]  NM_001008530, NM_005606
Rat[1]  NM_022226, NM_005606

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9742219
9821970
9891971
10349636
10725249
11042159
11076861
11217851
12466851
12477932
12775715
12904583
14610273
15044380
15782199
15905550
16141072
16141073
17350006
18374643
18799693
19106291
19879164
20164435
20234379
20495178
21267068
21292981
21606482
22718532
22916010
23237799
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0040015  negative regulation of multicellular organism growth
GO:0043524  negative regulation of neuron apoptosis
GO:0006508  proteolysis
GO:0001101  response to acid

Cellular Component

GO:0045177  apical part of cell
GO:0005770  late endosome
GO:0005764  lysosome

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0008234  cysteine-type peptidase activity
GO:0016787  hydrolase activity
GO:0008233  peptidase activity