Kruppel-like factor 11

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Synonym

9830142A17, D12Ertd427e, TGFB inducible early growth response 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:55.60 cerebellum:184.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:47.30 retina:96.40 eye:30.40 artery/aorta:421.90 vein:- lymphnode:- peripheral blood:129.40 spleen:13.20 thymus:108.70 bone marrow:- adipose:- bone:87.70 skin:63.30
GeneChip nodata
CAGE cerebrum:1.41 cerebellum:- brain stem:1.34 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.70 retina:- eye:- artery/aorta:2.79 vein:- lymphnode:2.05 peripheral blood:- spleen:2.93 thymus:1.63 bone marrow:- adipose:- bone:2.77 skin:2.43
RNA-seq cerebrum:1.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:41.40 prostate:- ovary:229.80 testis:29.60 heart:111.60 muscle:- esophagus:- stomach:- intestine:- colon:70.50     liver/hepato:54.30        lung:80.30    bladder:132.40 kidney:32.20 pituitary:64.60 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:71.80 salivary:-
GeneChip nodata
CAGE uterus:2.67 placenta:3.27 prostate:2.41 ovary:3.10 testis:1.48 heart:- muscle:- esophagus:- stomach:2.26 intestine:1.70 colon:1.96     liver/hepato:1.89    lung:3.34 bladder:2.65 kidney:- pituitary:1.48 thyroid/parathyroid:- adrenal gland:2.48 pancreas:1.30 breast:2.22 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.32 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.08        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_178357
Gene ID 194655
Unigene ID Mm.9616
Probe set ID -
Ensembl ID ENSMUSG00000020653

Orthologous Gene

Human[2]  NM_001177716, NM_001177718, NM_003597
Rat[1]  NM_001037354, NM_001177718, NM_003597

Chromosomal Region

12A1.3  [25,336,236  -  25,347,639]

Gene Family (Interpro ID)

IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

10349636
10725249
10922068
10973969
11042159
11076861
11087666
11217851
12466851
12477932
12970187
14697507
15300592
15489334
15607700
15618518
15820306
16141072
16141073
17015433
18189266
18287559
20059953
20060466
20201061
20412781
21267068
21592955
21677750
22628545
23042817
23183531
23408111
23555910
24069400
24333413

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0030097  hemopoiesis
GO:0008285  negative regulation of cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0043065  positive regulation of apoptosis
GO:0000115  regulation of transcription involved in S-phase of mitotic cell cycle
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0046872  metal ion binding
GO:0003676  nucleic acid binding
GO:0003700  transcription factor activity