secreted frizzled-related protein 4

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Synonym

Sfrp4, secreted frizzled-related sequence protein 4, FRP-4, sFRP-4, Frizzled-related protein 4

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:10.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:248.40

spine:-

retina:64.30

eye:-

artery/aorta:253.20

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:50.10

skin:63.30

GeneChip

cerebrum:7.23

cerebellum:7.22

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.81

spine:7.43

retina:7.11

eye:7.18

artery/aorta:-

vein:9.55

lymphnode:7.07

peripheral blood:-

spleen:7.05

thymus:-

bone marrow:8.67

adipose:7.56

bone:9.05

skin:7.02

CAGE

cerebrum:0.86

cerebellum:-

brain stem:0.94

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.11

retina:-

eye:-

artery/aorta:4.02

vein:-

lymphnode:0.23

peripheral blood:-

spleen:0.41

thymus:0.27

bone marrow:-

adipose:-

bone:3.44

skin:2.26

RNA-seq

cerebrum:0.64

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:130.90

placenta:82.80

prostate:-

ovary:-

testis:36.90

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:66.20

kidney:-

pituitary:25.80

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:3.30

salivary:-

GeneChip

uterus:10.72

placenta:9.81

prostate:7.16

ovary:12.89

testis:7.36

heart:7.44

muscle:7.67

esophagus:-

stomach:7.47

intestine:7.09

colon:-

liver/hepato:7.39

lung:6.94

bladder:7.51

kidney:7.58

pituitary:7.90

thyroid/parathyroid:-

adrenal gland:7.10

pancreas:6.90

breast:8.29

salivary:7.63

CAGE

uterus:4.35

placenta:4.99

prostate:0.63

ovary:6.41

testis:0

heart:-

muscle:-

esophagus:-

stomach:1.07

intestine:0.72

colon:0.41

liver/hepato:0

lung:0.98

bladder:1.31

kidney:-

pituitary:2.50

thyroid/parathyroid:-

adrenal gland:1.34

pancreas:0.84

breast:1.89

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.70

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_016687
Gene ID	20379
Unigene ID	Mm.42095
Probe set ID	1451031_at [Mouse430_2]
Ensembl ID	ENSMUSG00000021319

Orthologous Gene

Human[2]	NM_003014
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR020067	Frizzled-like domain
IPR001134	Netrin domain
IPR018933	Netrin module, non-TIMP type
IPR008993	TIMP-like, OB-fold

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0007420	brain development
GO:0030154	cell differentiation
GO:0046697	decidualization
GO:0009790	embryonic development
GO:0060429	epithelium development
GO:0008406	gonad development
GO:0060056	mammary gland involution
GO:0007275	multicellular organismal development
GO:0008285	negative regulation of cell proliferation
GO:0046329	negative regulation of JNK cascade
GO:0043433	negative regulation of transcription factor activity
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0055062	phosphate ion homeostasis
GO:0043065	positive regulation of apoptosis
GO:0045606	positive regulation of epidermal cell differentiation
GO:0010628	positive regulation of gene expression
GO:0002092	positive regulation of receptor internalization
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0001944	vasculature development
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus

Molecular Function

GO:0030165	PDZ domain binding
GO:0042813	Wnt receptor activity
GO:0017147	Wnt-protein binding

secreted frizzled-related protein 4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function