synaptotagmin III

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Synonym

Synaptotagmin III, syt III, synaptotagmin III, Syt3, SytIII, Synaptotagmin-3, AI385753

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59 cerebellum:92.10 brain stem:95.30 corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:94.60 retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.95 cerebellum:5.83 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.08 spine:7.12 retina:4.88 eye:5.09 artery/aorta:- vein:4.71 lymphnode:4.58 peripheral blood:- spleen:4.69 thymus:- bone marrow:4.79 adipose:4.97 bone:4.47 skin:4.78
CAGE cerebrum:3.61 cerebellum:- brain stem:3.69 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.05 retina:- eye:- artery/aorta:1.36 vein:- lymphnode:0.42 peripheral blood:- spleen:0.16 thymus:0.27 bone marrow:- adipose:- bone:0 skin:1.03
RNA-seq cerebrum:10.98 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:3.30 salivary:54
GeneChip uterus:4.57 placenta:4.70 prostate:5.09 ovary:4.49 testis:4.94 heart:5.05 muscle:5.07 esophagus:- stomach:4.67 intestine:4.69 colon:- liver/hepato:5.54 lung:4.68 bladder:4.75 kidney:5 pituitary:5.15 thyroid/parathyroid:- adrenal gland:4.69 pancreas:6.37 breast:4.83 salivary:5.61
CAGE uterus:0.74 placenta:0 prostate:1.16 ovary:0.45 testis:0 heart:- muscle:- esophagus:- stomach:1.35 intestine:0 colon:0.82     liver/hepato:1.70    lung:0.55 bladder:1.26 kidney:- pituitary:2.01 thyroid/parathyroid:- adrenal gland:1.38 pancreas:3.10 breast:0.30 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.31 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.02        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_016663
Gene ID 20981
Unigene ID Mm.4824
Probe set ID 1417708_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030731

Orthologous Gene

Human[3]  NM_001160328, NM_001160329, NM_032298
Rat [0]  

Chromosomal Region

7B4  [51,639,472  -  51,655,557]

Gene Family (Interpro ID)

IPR000008  C2 calcium-dependent membrane targeting
IPR008973  C2 calcium/lipid-binding domain, CaLB
IPR018029  C2 membrane targeting protein

Link to Pubmed  (Pubmed ID)

1495973
2132728
7592870
7749232
8058779
8617498
8653788
8747928
8812484
9166596
9457670
9615230
9914469
10531343
10753658
12466851
12477932
12828934
14610273
14681479
15350218
15489334
16407767
16602821
17179206
18799693
20002670
21267068
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0031340  positive regulation of vesicle fusion
GO:0051592  response to calcium ion
GO:0006810  transport

Cellular Component

GO:0030054  cell junction
GO:0031410  cytoplasmic vesicle
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0045202  synapse
GO:0008021  synaptic vesicle

Molecular Function

GO:0005544  calcium-dependent phospholipid binding
GO:0030276  clathrin binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0001786  phosphatidylserine binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0000149  SNARE binding
GO:0019905  syntaxin binding
GO:0005215  transporter activity