alkB, alkylation repair homolog 1 (E. coli)

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Synonym

Alkbh, 2700073G19Rik, alkB, hABH, Alkbh1, alkB, alkylation repair homolog 1 (E. coli)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12.20 cerebellum:18.40 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:47.30 retina:32.10 eye:38 artery/aorta:- vein:- lymphnode:- peripheral blood:28.80 spleen:13.20 thymus:59.30 bone marrow:- adipose:- bone:25 skin:23.80
GeneChip nodata
CAGE cerebrum:2.77 cerebellum:- brain stem:2.45 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.51 retina:- eye:- artery/aorta:2.79 vein:- lymphnode:4.16 peripheral blood:- spleen:3.21 thymus:3.36 bone marrow:- adipose:- bone:2.97 skin:3.49
RNA-seq cerebrum:1.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:34.50 testis:81.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:40.20    bladder:66.20 kidney:24.20 pituitary:38.80 thyroid/parathyroid:- adrenal gland:- pancreas:75.10 breast:19.60 salivary:-
GeneChip nodata
CAGE uterus:3.46 placenta:2.62 prostate:2.54 ovary:3.32 testis:2.85 heart:- muscle:- esophagus:- stomach:2.36 intestine:2.67 colon:2.71     liver/hepato:2.87    lung:2.74 bladder:2.64 kidney:- pituitary:3.44 thyroid/parathyroid:- adrenal gland:2.98 pancreas:2.83 breast:3.31 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.39        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001102565
Gene ID 211064
Unigene ID Mm.26840
Probe set ID -
Ensembl ID ENSMUSG00000079036

Orthologous Gene

Human[1]  NM_006020
Rat[1]  NM_001108718

Chromosomal Region

12D2  [88,767,119  -  88,784,789]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
10922068
11042159
11076861
11217851
12466851
12477932
14610273
16141072
16141073
16860792
18163532
18799693
19468303
21072209
21267068
22961808
22965116
23825659

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0048589  developmental growth
GO:0006307  DNA dealkylation
GO:0080111  DNA demethylation
GO:0006281  DNA repair
GO:0001701  in utero embryonic development
GO:0008152  metabolic process
GO:0043524  negative regulation of neuron apoptosis
GO:0001764  neuron migration
GO:0031175  neuron projection development
GO:0055114  oxidation reduction
GO:0070989  oxidative demethylation
GO:0001890  placenta development
GO:0050918  positive chemotaxis
GO:0010468  regulation of gene expression
GO:0006974  response to DNA damage stimulus
GO:0042245  RNA repair

Cellular Component

GO:0005739  mitochondrion
GO:0005719  nuclear euchromatin
GO:0005634  nucleus

Molecular Function

GO:0003824  catalytic activity
GO:0042056  chemoattractant activity
GO:0003906  DNA-(apurinic or apyrimidinic site) lyase activity
GO:0008198  ferrous iron binding
GO:0016829  lyase activity
GO:0046872  metal ion binding
GO:0070579  methylcytosine dioxygenase activity
GO:0016491  oxidoreductase activity
GO:0016706  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0005515  protein binding