RAS protein activator like 2

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Synonym

RAS protein activator like 2, Rasal2, 6530401P13, A330066M24Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12.20 cerebellum:110.50 brain stem:127.10 corpus callosum/glia:- pineal gland:- peripheral nerve:76.40 spine:283.70 retina:32.10 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:7.90
GeneChip cerebrum:9.06 cerebellum:8.44 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.37 spine:8.93 retina:7.52 eye:6.67 artery/aorta:- vein:7.31 lymphnode:6.46 peripheral blood:- spleen:6.59 thymus:- bone marrow:5.01 adipose:7.07 bone:5.76 skin:8.21
CAGE cerebrum:3.14 cerebellum:- brain stem:3.01 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.20 retina:- eye:- artery/aorta:2.67 vein:- lymphnode:1.03 peripheral blood:- spleen:1.12 thymus:1.17 bone marrow:- adipose:- bone:1.69 skin:2.92
RNA-seq cerebrum:1.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:11.50 testis:51.70 heart:55.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:50.20    bladder:- kidney:32.20 pituitary:38.80 thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:22.90 salivary:-
GeneChip uterus:7.06 placenta:6.25 prostate:6.48 ovary:7.22 testis:8.66 heart:8.64 muscle:7.21 esophagus:- stomach:6.96 intestine:6.91 colon:- liver/hepato:7.38 lung:8.91 bladder:8.16 kidney:7.59 pituitary:8.47 thyroid/parathyroid:- adrenal gland:7.22 pancreas:7.15 breast:6.92 salivary:6.62
CAGE uterus:2.12 placenta:1.96 prostate:1.35 ovary:2.61 testis:3.47 heart:- muscle:- esophagus:- stomach:0.67 intestine:1.84 colon:2.07     liver/hepato:2.76    lung:3.27 bladder:2.55 kidney:- pituitary:3.11 thyroid/parathyroid:- adrenal gland:2.58 pancreas:2.56 breast:2.17 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.28 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.26        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_177644
Gene ID 226525
Unigene ID Mm.235028
Probe set ID 1436910_at  [Mouse430_2]
Ensembl ID ENSMUSG00000070565

Orthologous Gene

Human[4]  NM_004841, NM_170692
Rat[1]  NM_001107188, NM_170692

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000008  C2 calcium-dependent membrane targeting
IPR008973  C2 calcium/lipid-binding domain, CaLB
IPR001849  Pleckstrin homology
IPR001936  Ras GTPase-activating protein
IPR008936  Rho GTPase activation protein

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
12466851
12477932
12904583
16141072
16141073
21267068
21677750
24029233

Gene Ontology  (GO ID)

Biological Process

GO:0046580  negative regulation of Ras protein signal transduction
GO:0032320  positive regulation of Ras GTPase activity

Cellular Component

GO:0005737  cytoplasm
GO:0031235  intrinsic to internal side of plasma membrane

Molecular Function

GO:0005096  GTPase activator activity
GO:0005099  Ras GTPase activator activity