ubiquitin specific peptidase 1

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Synonym

ubiquitin specific peptdiase 1, MGC25559, Usp1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45.20 cerebellum:294.70 brain stem:222.50 corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:- retina:192.90 eye:83.60 artery/aorta:84.40 vein:- lymphnode:75.60 peripheral blood:43.10 spleen:118.50 thymus:118.60 bone marrow:12.80 adipose:638.20 bone:50.10 skin:118.80
GeneChip cerebrum:8.19 cerebellum:8.69 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.51 spine:7.23 retina:8.98 eye:9.62 artery/aorta:- vein:9.68 lymphnode:10.13 peripheral blood:- spleen:10.01 thymus:- bone marrow:11.34 adipose:8.56 bone:11.28 skin:9.55
CAGE cerebrum:2.64 cerebellum:- brain stem:2.15 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.64 retina:- eye:- artery/aorta:2.89 vein:- lymphnode:3.20 peripheral blood:- spleen:3.96 thymus:3.76 bone marrow:- adipose:- bone:3.44 skin:3.10
RNA-seq cerebrum:1.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:124.30 prostate:61.80 ovary:183.90 testis:303 heart:18.60 muscle:- esophagus:- stomach:65.50 intestine:- colon:17.60     liver/hepato:9.10        lung:80.30    bladder:66.20 kidney:24.20 pituitary:400.40 thyroid/parathyroid:- adrenal gland:- pancreas:84.40 breast:81.60 salivary:-
GeneChip uterus:10.08 placenta:9.80 prostate:8.81 ovary:9.73 testis:11.99 heart:7.88 muscle:8.13 esophagus:- stomach:8.81 intestine:9.52 colon:- liver/hepato:8.42 lung:9.09 bladder:9.04 kidney:8.40 pituitary:8.74 thyroid/parathyroid:- adrenal gland:8.12 pancreas:9.11 breast:8.95 salivary:8.29
CAGE uterus:3.14 placenta:3.71 prostate:2.43 ovary:2.99 testis:6.64 heart:- muscle:- esophagus:- stomach:2.36 intestine:3.46 colon:3.25     liver/hepato:2.68    lung:2.95 bladder:2.62 kidney:- pituitary:2.50 thyroid/parathyroid:- adrenal gland:2.59 pancreas:2.90 breast:3.26 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.87 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.32        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_146144
Gene ID 230484
Unigene ID Mm.371692
Probe set ID 1451080_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028560

Orthologous Gene

Human[6]  NM_001017415, NM_001017416, NM_003368
Rat[1]  NM_001015015, NM_001017416, NM_003368

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
12466851
12477932
12904583
14610273
15226823
15760467
16141072
16141073
18799693
19217432
20506303
21677750
21925315
23159736
23806336
24001775
24005329
24573694

Gene Ontology  (GO ID)

Biological Process

GO:0006281  DNA repair
GO:0016579  protein deubiquitination
GO:0006508  proteolysis
GO:0006282  regulation of DNA repair
GO:0006974  response to DNA damage stimulus
GO:0009411  response to UV
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0008234  cysteine-type peptidase activity
GO:0016787  hydrolase activity
GO:0008233  peptidase activity
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity