TNFAIP3 interacting protein 2

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Synonym

TNFAIP3 interacting protein 2, AI428870, Tnip2, ABIN-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:18.40 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:22.80 artery/aorta:- vein:- lymphnode:54 peripheral blood:172.50 spleen:- thymus:69.20 bone marrow:76.90 adipose:- bone:37.60 skin:15.80
GeneChip cerebrum:5.72 cerebellum:4.82 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.06 spine:5.51 retina:5.39 eye:5.35 artery/aorta:- vein:5.65 lymphnode:6.76 peripheral blood:- spleen:6.29 thymus:- bone marrow:5.30 adipose:5.68 bone:5.50 skin:6.50
CAGE cerebrum:1.53 cerebellum:- brain stem:1.78 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.82 retina:- eye:- artery/aorta:2.50 vein:- lymphnode:2.95 peripheral blood:- spleen:2.26 thymus:1.80 bone marrow:- adipose:- bone:1.69 skin:3.37
RNA-seq cerebrum:1.53 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:27.60 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:20.10    bladder:- kidney:32.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:9.40 breast:9.80 salivary:-
GeneChip uterus:6.70 placenta:5.59 prostate:6.97 ovary:6.20 testis:5.04 heart:5.67 muscle:5.82 esophagus:- stomach:5.82 intestine:5.70 colon:- liver/hepato:5.54 lung:6.39 bladder:6.08 kidney:5.48 pituitary:5.37 thyroid/parathyroid:- adrenal gland:6.06 pancreas:5.46 breast:5.97 salivary:5.90
CAGE uterus:3.21 placenta:1.82 prostate:3.08 ovary:2.57 testis:1.34 heart:- muscle:- esophagus:- stomach:2.04 intestine:1.65 colon:1.81     liver/hepato:2.20    lung:3.02 bladder:2.86 kidney:- pituitary:2.25 thyroid/parathyroid:- adrenal gland:2.48 pancreas:2.66 breast:2.70 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.53 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_139064
Gene ID 231130
Unigene ID Mm.28615
Probe set ID 1419488_at  [Mouse430_2]
Ensembl ID ENSMUSG00000059866

Orthologous Gene

Human[4]  NM_001161527, NM_024309
Rat[1]  NM_001024771, NM_024309

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
11390377
12466851
12477932
14610273
15169888
16141072
16141073
16480954
16633345
21677750
21784860
24639351

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0071222  cellular response to lipopolysaccharide
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0006954  inflammatory response
GO:0070498  interleukin-1-mediated signaling pathway
GO:0050871  positive regulation of B cell activation
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043032  positive regulation of macrophage activation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0050821  protein stabilization
GO:0006355  regulation of transcription, DNA-dependent
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0031593  polyubiquitin binding
GO:0005515  protein binding
GO:0019901  protein kinase binding