Wolf-Hirschhorn syndrome candidate 1-like 1 (human)

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Synonym

WHISTLE, NSD3, 6720429E03, AI528490, A530023P05, Whsc1l1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:76.40 cerebellum:18.40 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:257.20 eye:22.80 artery/aorta:253.20 vein:- lymphnode:118.80 peripheral blood:244.40 spleen:289.70 thymus:79 bone marrow:38.50 adipose:- bone:25 skin:79.20
GeneChip nodata
CAGE cerebrum:3.33 cerebellum:- brain stem:3.02 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.05 retina:- eye:- artery/aorta:3.44 vein:- lymphnode:4.42 peripheral blood:- spleen:3.67 thymus:3.22 bone marrow:- adipose:- bone:3.64 skin:3.84
RNA-seq cerebrum:4.77 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:27.60 prostate:61.80 ovary:23 testis:51.70 heart:37.20 muscle:71 esophagus:- stomach:196.40 intestine:110.90 colon:158.60     liver/hepato:36.20        lung:40.20    bladder:- kidney:- pituitary:335.80 thyroid/parathyroid:112.50 adrenal gland:- pancreas:93.80 breast:49 salivary:-
GeneChip nodata
CAGE uterus:3.22 placenta:4.23 prostate:3.65 ovary:3.02 testis:3.25 heart:- muscle:- esophagus:- stomach:2.95 intestine:3.05 colon:3.04     liver/hepato:3.78    lung:3.72 bladder:3.36 kidney:- pituitary:3.28 thyroid/parathyroid:- adrenal gland:3.39 pancreas:4.45 breast:3.61 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.91 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.93        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001081269
Gene ID 234135
Unigene ID Mm.217337
Probe set ID -
Ensembl ID ENSMUSG00000054823

Orthologous Gene

Human[2]  NM_017778, NM_023034
Rat[1]  NM_001106090, NM_023034

Chromosomal Region

8A2  [26,712,073  -  26,830,139]

Gene Family (Interpro ID)

IPR019787  Zinc finger, PHD-finger
IPR001965  Zinc finger, PHD-type

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
12466851
12477932
12904583
14610273
15489334
16141072
16141073
16682010
17239852
17967808
18287559
20530532
22421440
22922362

Gene Ontology  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0034968  histone lysine methylation
GO:0016571  histone methylation
GO:0032259  methylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005694  chromosome
GO:0005634  nucleus

Molecular Function

GO:0018024  histone-lysine N-methyltransferase activity
GO:0046872  metal ion binding
GO:0008168  methyltransferase activity
GO:0016740  transferase activity
GO:0008270  zinc ion binding