inositol polyphosphate-4-phosphatase, type II

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Synonym

Inositol polyphosphate 4-phosphatase type II, Type II inositol-3,4-bisphosphate 4-phosphatase, E130107I17Rik, Inpp4b, inositol polyphosphate-4-phosphatase, type II

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:94.60 retina:32.10 eye:38 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:14.40 spleen:158 thymus:49.40 bone marrow:25.60 adipose:212.70 bone:- skin:-
GeneChip nodata
CAGE cerebrum:3.52 cerebellum:- brain stem:3.27 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.20 retina:- eye:- artery/aorta:2.33 vein:- lymphnode:5.44 peripheral blood:- spleen:3.58 thymus:3.80 bone marrow:- adipose:- bone:2.45 skin:2.73
RNA-seq cerebrum:1.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:37.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:20.10    bladder:66.20 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:28.10 breast:13.10 salivary:-
GeneChip nodata
CAGE uterus:2.77 placenta:0.88 prostate:1.16 ovary:2.11 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:1.05 colon:2.24     liver/hepato:0.78    lung:2.84 bladder:1.76 kidney:- pituitary:1.40 thyroid/parathyroid:- adrenal gland:2.13 pancreas:2.33 breast:2.55 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.28 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0.91        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001024617
Gene ID 234515
Unigene ID Mm.324468
Probe set ID -
Ensembl ID ENSMUSG00000037940

Orthologous Gene

Human[2]  NM_001101669, NM_003866
Rat [0]  

Chromosomal Region

8C2  [83,866,455  -  84,648,935]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
12466851
12477932
14681479
15489334
16141072
16141073
16247441
16631325
21267068
21982707
23078915

Gene Ontology  (GO ID)

Biological Process

GO:0006874  cellular calcium ion homeostasis
GO:0046855  inositol phosphate dephosphorylation
GO:0045671  negative regulation of osteoclast differentiation
GO:0046856  phosphoinositide dephosphorylation
GO:0046850  regulation of bone remodeling
GO:0046822  regulation of nucleocytoplasmic transport
GO:0051896  regulation of protein kinase B signaling cascade

Cellular Component

GO:0005737  cytoplasm
GO:0005794  Golgi apparatus

Molecular Function

GO:0016787  hydrolase activity
GO:0008289  lipid binding
GO:0034597  phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity
GO:0034593  phosphatidylinositol bisphosphate phosphatase activity
GO:0034594  phosphatidylinositol trisphosphate phosphatase activity
GO:0016316  phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity