3-phosphoglycerate dehydrogenase

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Synonym

PGD, 3-PGDH, MGC117966, PGAD, 3-phosphoglycerate dehydrogenase, Phgdh, PGDH, A10, 4930479N23, D-3-phosphoglycerate dehydrogenase, 3PGDH, SERA, MGC113796

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:114.60 cerebellum:239.50 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:- retina:32.10 eye:106.40 artery/aorta:84.40 vein:- lymphnode:10.80 peripheral blood:172.50 spleen:13.20 thymus:158.10 bone marrow:205.10 adipose:212.70 bone:125.20 skin:213.80
GeneChip cerebrum:9.21 cerebellum:8.84 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.89 spine:9.74 retina:9.07 eye:9.26 artery/aorta:- vein:8.73 lymphnode:9.39 peripheral blood:- spleen:9.29 thymus:- bone marrow:8.95 adipose:10.35 bone:8.67 skin:9.01
CAGE cerebrum:1.38 cerebellum:- brain stem:1.56 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.66 retina:- eye:- artery/aorta:1.20 vein:- lymphnode:1.20 peripheral blood:- spleen:1.76 thymus:2.03 bone marrow:- adipose:- bone:1.51 skin:0.91
RNA-seq cerebrum:18.54 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:261.70 placenta:55.20 prostate:- ovary:34.50 testis:44.30 heart:93 muscle:248.60 esophagus:- stomach:98.20 intestine:- colon:17.60     liver/hepato:18.10        lung:140.60    bladder:529.50 kidney:129 pituitary:103.30 thyroid/parathyroid:112.50 adrenal gland:- pancreas:65.70 breast:140.40 salivary:432
GeneChip uterus:7.98 placenta:8.82 prostate:11.17 ovary:9.06 testis:8.39 heart:6.54 muscle:7.11 esophagus:- stomach:8.65 intestine:7.49 colon:- liver/hepato:5.92 lung:6.87 bladder:7.13 kidney:7.70 pituitary:7.94 thyroid/parathyroid:- adrenal gland:7.42 pancreas:12.18 breast:9.41 salivary:11.40
CAGE uterus:0.55 placenta:1.63 prostate:2.56 ovary:0.99 testis:0.99 heart:- muscle:- esophagus:- stomach:1.35 intestine:1.49 colon:1.11     liver/hepato:0    lung:0 bladder:0.77 kidney:- pituitary:0.29 thyroid/parathyroid:- adrenal gland:0.64 pancreas:3.41 breast:1.80 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.98 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.29        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_016966
Gene ID 236539
Unigene ID Mm.16898
Probe set ID 1454714_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000053398

Orthologous Gene

Human [0]  
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7682653
10349636
10713460
10922068
11042159
11076861
11217851
11567059
12466851
12477932
12533615
14610273
14645240
14681479
15139021
15256251
15489334
15782199
16141072
16141073
17510490
18228065
18751891
19114063
19429008
19778996
20697350
20966073
21677750
22371338
22438825
23350942
23666531
23884950
24434753
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0008652  cellular amino acid biosynthetic process
GO:0070314  G1 to G0 transition
GO:0009448  gamma-aminobutyric acid metabolic process
GO:0021782  glial cell development
GO:0006541  glutamine metabolic process
GO:0006544  glycine metabolic process
GO:0006564  L-serine biosynthetic process
GO:0006563  L-serine metabolic process
GO:0008152  metabolic process
GO:0021915  neural tube development
GO:0022008  neurogenesis
GO:0031175  neuron projection development
GO:0055114  oxidation reduction
GO:0010468  regulation of gene expression
GO:0021510  spinal cord development
GO:0019530  taurine metabolic process
GO:0006566  threonine metabolic process

Molecular Function

GO:0048037  cofactor binding
GO:0051287  NAD or NADH binding
GO:0016491  oxidoreductase activity
GO:0016616  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004617  phosphoglycerate dehydrogenase activity