A kinase (PRKA) anchor protein 6

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Synonym

A kinase (PRKA) anchor protein 6, Akapbeta, Akapalpha, Akap6, anchor protein 6, AI482140, MGC73457, PRKA

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59 cerebellum:55.30 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:47.30 retina:160.70 eye:38 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:25 skin:-
GeneChip nodata
CAGE cerebrum:4.96 cerebellum:- brain stem:5.19 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.29 retina:- eye:- artery/aorta:1.28 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:2.19 skin:2.54
RNA-seq cerebrum:4.53 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:- testis:- heart:93 muscle:71 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:6.50 salivary:-
GeneChip nodata
CAGE uterus:0.17 placenta:0 prostate:1.87 ovary:0.13 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:0 colon:0.70     liver/hepato:0    lung:1.17 bladder:1.62 kidney:- pituitary:1.56 thyroid/parathyroid:- adrenal gland:1.77 pancreas:0 breast:0.32 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.36 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_198111
Gene ID 238161
Unigene ID Mm.310822
Probe set ID -
Ensembl ID ENSMUSG00000061603

Orthologous Gene

Human[2]  NM_004274
Rat [0]  

Chromosomal Region

12C1  [53,800,370  -  54,252,002]

Gene Family (Interpro ID)

IPR018159  Spectrin/alpha-actinin

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11544199
11590243
12466851
12477932
14621295
16141072
16141073
16337591
16602821
18799693
19574217
21267068
23261540

Gene Ontology  (GO ID)

Biological Process

GO:0071320  cellular response to cAMP
GO:0030818  negative regulation of cAMP biosynthetic process
GO:0016310  phosphorylation
GO:0032514  positive regulation of protein phosphatase type 2B activity
GO:0060306  regulation of membrane repolarization
GO:0010738  regulation of protein kinase A signaling cascade

Cellular Component

GO:0034704  calcium channel complex
GO:0005901  caveola
GO:0005737  cytoplasm
GO:0005635  nuclear envelope
GO:0031965  nuclear membrane
GO:0005640  nuclear outer membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0043234  protein complex
GO:0016529  sarcoplasmic reticulum

Molecular Function

GO:0019899  enzyme binding
GO:0016301  kinase activity
GO:0032947  protein complex scaffold
GO:0051018  protein kinase A binding
GO:0034237  protein kinase A regulatory subunit binding
GO:0047485  protein N-terminus binding
GO:0016740  transferase activity