Eph receptor B1

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Synonym

Net, Elk, Cek6, Eph receptor B1, Elkh, Hek6, Ephb1, AW488255, 9330129L11

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:60.80 cerebellum:184.20 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:47.30 retina:- eye:30.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.50 skin:23.80
GeneChip nodata
CAGE cerebrum:4.44 cerebellum:- brain stem:4.45 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.77 retina:- eye:- artery/aorta:2.55 vein:- lymphnode:1.59 peripheral blood:- spleen:0.41 thymus:0 bone marrow:- adipose:- bone:0 skin:3.65
RNA-seq cerebrum:7.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:7.40 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:20.10    bladder:- kidney:- pituitary:64.60 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip nodata
CAGE uterus:1.87 placenta:1.67 prostate:0.84 ovary:2.30 testis:0 heart:- muscle:- esophagus:- stomach:1.07 intestine:0.72 colon:1.11     liver/hepato:0.47    lung:1.11 bladder:1.31 kidney:- pituitary:1.86 thyroid/parathyroid:- adrenal gland:1.52 pancreas:0 breast:1.75 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.21 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_173447
Gene ID 270190
Unigene ID Mm.22897
Probe set ID -
Ensembl ID ENSMUSG00000032537

Orthologous Gene

Human[2]  NM_004441
Rat[1]  NM_001104528

Chromosomal Region

9F1  [101,824,458  -  102,257,023]

Gene Family (Interpro ID)

IPR001090  Ephrin receptor, ligand binding
IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR008979  Galactose-binding domain-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR013761  Sterile alpha motif-type
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR016257  Tyrosine-protein kinase, ephrin receptor
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

7609620
8798570
8889548
9267020
10207129
10349636
10495276
10625551
10683176
10704386
10705993
10729342
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17638910
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18034775
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21964490
22103419
22171039
22365545
22434763
22475621
22492037
22622783
22879882
23129351
23143520
23147113
23318582
23341972
23558405
23578932
23649798
23884953
23973554
24038449
24453220

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0007411  axon guidance
GO:0048593  camera-type eye morphogenesis
GO:0007155  cell adhesion
GO:0060326  cell chemotaxis
GO:0031589  cell-substrate adhesion
GO:0021952  central nervous system projection neuron axonogenesis
GO:0021545  cranial nerve development
GO:0050965  detection of temperature stimulus involved in sensory perception of pain
GO:0048013  ephrin receptor signaling pathway
GO:0030010  establishment of cell polarity
GO:0007399  nervous system development
GO:0022008  neurogenesis
GO:0021631  optic nerve morphogenesis
GO:0016310  phosphorylation
GO:0051965  positive regulation of synaptogenesis
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0046328  regulation of JNK cascade
GO:0031290  retinal ganglion cell axon guidance
GO:0007165  signal transduction
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0030424  axon
GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0031901  early endosome membrane
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0008046  axon guidance receptor activity
GO:0005003  ephrin receptor activity
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0005005  transmembrane-ephrin receptor activity