Ca2+-dependent secretion activator

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Synonym

mKIAA1121, Calcium-dependent secretion activator 1, Kiaa1121, CAPS-1, AU067781, CAPS, Caps1, Ca<2+>dependent activator protein for secretion, CAPS1, Caps, MGC90712, Cadps

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:99 cerebellum:110.50 brain stem:63.60 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:38.20 spine:- retina:96.40 eye:144.40 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:- spleen:52.70 thymus:19.80 bone marrow:- adipose:- bone:12.50 skin:7.90
GeneChip cerebrum:11.02 cerebellum:10.57 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:12.25 spine:11.64 retina:9.51 eye:5.60 artery/aorta:- vein:4.78 lymphnode:3.88 peripheral blood:- spleen:4.39 thymus:- bone marrow:4.15 adipose:4.01 bone:4.15 skin:3.93
CAGE cerebrum:4.80 cerebellum:- brain stem:5.27 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.27 retina:- eye:- artery/aorta:0.14 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0.67 bone marrow:- adipose:- bone:0 skin:0.97
RNA-seq cerebrum:18.25 cerebellum:18.25 brain stem:18.25 corpus callosum/glia:18.25 pineal gland:18.25 peripheral nerve:18.25 spine:18.25 retina:18.25 eye:18.25 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:14.80 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:75.10 breast:- salivary:-
GeneChip uterus:4.09 placenta:4.08 prostate:4.54 ovary:4.03 testis:4.27 heart:4.29 muscle:4.03 esophagus:- stomach:4.62 intestine:4.82 colon:- liver/hepato:4.18 lung:3.94 bladder:4.87 kidney:4.01 pituitary:9.15 thyroid/parathyroid:- adrenal gland:7.40 pancreas:5.93 breast:4.09 salivary:4.28
CAGE uterus:0.74 placenta:0 prostate:1.60 ovary:0.13 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0.84 colon:1.19     liver/hepato:0    lung:0 bladder:1.62 kidney:- pituitary:3.88 thyroid/parathyroid:- adrenal gland:2.60 pancreas:1.84 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_012061
Gene ID 27062
Unigene ID Mm.260881
Probe set ID 1448955_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000054423

Orthologous Gene

Human[3]  NM_003716, NM_183393, NM_183394
Rat[1]  NM_013219, NM_183393, NM_183394

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
12466851
12477932
12659812
12693553
14530279
14715936
15226823
15489334
15820695
16141072
16141073
16506193
16602821
17540763
18022372
18177725
18495893
18554416
19008227
19238500
19460754
20400514
20855507
20921225
21040848
21267068
22111578
22235033
22357600
23055939
23801330
24154525
24174665

Gene Ontology  (GO ID)

Biological Process

GO:0050432  catecholamine secretion
GO:0006887  exocytosis
GO:0045956  positive regulation of calcium ion-dependent exocytosis
GO:0015031  protein transport
GO:0016082  synaptic vesicle priming
GO:0006810  transport
GO:0016050  vesicle organization

Cellular Component

GO:0030054  cell junction
GO:0031410  cytoplasmic vesicle
GO:0016020  membrane
GO:0045202  synapse

Molecular Function

GO:0005509  calcium ion binding
GO:0008289  lipid binding
GO:0046872  metal ion binding
GO:0005543  phospholipid binding
GO:0005515  protein binding