Rho GTPase-activating protein

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Synonym

KIAA0712, RICS, p200RhoGAP, GC-GAP, Grit, Rho GTPase-activating protein, mKIAA0712

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:2.04 cerebellum:- brain stem:2.28 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.44 retina:- eye:- artery/aorta:0.95 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0.67 bone marrow:- adipose:- bone:0 skin:4.05
RNA-seq cerebrum:9.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:3.84 placenta:0.75 prostate:3.59 ovary:2.64 testis:0 heart:- muscle:- esophagus:- stomach:3.05 intestine:4.27 colon:3.84     liver/hepato:0.47    lung:2.36 bladder:3.11 kidney:- pituitary:1.11 thyroid/parathyroid:- adrenal gland:0 pancreas:1.61 breast:2.51 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.32 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.63        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_177379
Gene ID 330914
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000041444

Orthologous Gene

Human[4]  NM_001142685, NM_014715
Rat[4]  NM_001142685, NM_014715

Chromosomal Region

9A4  [31,923,721  -  32,076,031]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
12454018
12466851
12477932
12520002
12531901
12819203
12857875
12904583
14610273
14691545
15368895
16141072
16141073
16602821
16716191
17272280
17663722
17967808
18218630
18331582
18451111
18799693
21267068
22315408
23226367
24431455

Gene Ontology  (GO ID)

Biological Process

GO:0007154  cell communication
GO:0007266  Rho protein signal transduction
GO:0007165  signal transduction

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005938  cell cortex
GO:0030054  cell junction
GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0005794  Golgi apparatus
GO:0005622  intracellular
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0045202  synapse

Molecular Function

GO:0005096  GTPase activator activity
GO:0035091  phosphoinositide binding