BR serine/threonine kinase 1

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Synonym

MGC99905, SAD-B, Brsk1, BR serine/threonine kinase 1, SADB, Gm1100

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:31.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:7.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.50 skin:7.90
GeneChip nodata
CAGE cerebrum:3.39 cerebellum:- brain stem:3.70 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.82 retina:- eye:- artery/aorta:0.46 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0.40
RNA-seq cerebrum:58.83 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:-        lung:10    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip nodata
CAGE uterus:0.83 placenta:0 prostate:0.37 ovary:0.88 testis:3.11 heart:- muscle:- esophagus:- stomach:0.67 intestine:0.42 colon:0.41     liver/hepato:0    lung:0.31 bladder:0.86 kidney:- pituitary:1.56 thyroid/parathyroid:- adrenal gland:0.71 pancreas:0 breast:0.50 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.82 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.81        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001003920
Gene ID 381979
Unigene ID Mm.297064
Probe set ID -
Ensembl ID ENSMUSG00000035390

Orthologous Gene

Human[1]  NM_032430
Rat [0]  

Chromosomal Region

7A1  [4,642,206  -  4,667,599]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain
IPR000449  Ubiquitin-associated/translation elongation factor EF1B, N-terminal
IPR015940  Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

Link to Pubmed  (Pubmed ID)

12477932
14610273
15489334
15705853
16944949
17482548
18227155
18614564
18794346
18799693
19648910
20026642
21490487
22020259
23790753
24395778

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0007049  cell cycle
GO:0051298  centrosome duplication
GO:0030010  establishment of cell polarity
GO:0031572  G2/M transition DNA damage checkpoint
GO:0000086  G2/M transition of mitotic cell cycle
GO:0007095  mitotic cell cycle G2/M transition DNA damage checkpoint
GO:0007399  nervous system development
GO:0030182  neuron differentiation
GO:0048812  neuron projection morphogenesis
GO:0007269  neurotransmitter secretion
GO:0018105  peptidyl-serine phosphorylation
GO:0016310  phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0006974  response to DNA damage stimulus
GO:0009411  response to UV

Cellular Component

GO:0030054  cell junction
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0045202  synapse
GO:0008021  synaptic vesicle

Molecular Function

GO:0005524  ATP binding
GO:0043015  gamma-tubulin binding
GO:0016301  kinase activity
GO:0000287  magnesium ion binding
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0050321  tau-protein kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups