thioredoxin reductase 1

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Synonym

TR alpha, Txnrd1, thioredoxin reductase 1, Thioredoxin reductase 1, cytoplasmic, TrxR1, Trxr1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:95.50

cerebellum:36.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:94.60

retina:96.40

eye:144.40

artery/aorta:-

vein:-

lymphnode:248.40

peripheral blood:86.30

spleen:65.80

thymus:79

bone marrow:230.80

adipose:425.40

bone:50.10

skin:95

GeneChip

cerebrum:8.82

cerebellum:8.70

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:9.76

spine:9.08

retina:7.95

eye:8.07

artery/aorta:-

vein:9.34

lymphnode:9.24

peripheral blood:-

spleen:8.99

thymus:-

bone marrow:9.31

adipose:9.37

bone:9.39

skin:9.95

CAGE

cerebrum:2.77

cerebellum:-

brain stem:3.16

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.17

retina:-

eye:-

artery/aorta:3.64

vein:-

lymphnode:3.65

peripheral blood:-

spleen:3.11

thymus:3.35

bone marrow:-

adipose:-

bone:3.32

skin:4.55

RNA-seq

cerebrum:8.57

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:55.20

prostate:-

ovary:23

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:130.90

intestine:110.90

colon:193.80

liver/hepato:63.40

lung:40.20

bladder:66.20

kidney:112.80

pituitary:116.30

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:46.90

breast:120.80

salivary:162

GeneChip

uterus:10.44

placenta:8.99

prostate:9.36

ovary:9.99

testis:8.29

heart:8.94

muscle:9.70

esophagus:-

stomach:10.52

intestine:11.02

colon:-

liver/hepato:10.26

lung:9.47

bladder:9.33

kidney:10.23

pituitary:9.47

thyroid/parathyroid:-

adrenal gland:9.24

pancreas:8.23

breast:9.60

salivary:8.82

CAGE

uterus:4.18

placenta:3.46

prostate:3.00

ovary:3.31

testis:1.18

heart:-

muscle:-

esophagus:-

stomach:4.13

intestine:5.34

colon:4.72

liver/hepato:4.57

lung:3.47

bladder:3.35

kidney:-

pituitary:3.32

thyroid/parathyroid:-

adrenal gland:3.39

pancreas:3.04

breast:4.05

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:8.75

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:15.98

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_015762
Gene ID	50493
Unigene ID	Mm.210155
Probe set ID	1421529_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000020250

Orthologous Gene

Human[5]	NM_001093771, NM_003330, NM_182729, NM_182742, NM_182743
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0042537	benzene and derivative metabolic process
GO:0008283	cell proliferation
GO:0045454	cell redox homeostasis
GO:0007369	gastrulation
GO:0042744	hydrogen peroxide catabolic process
GO:0001707	mesoderm formation
GO:0070995	NADPH oxidation
GO:0055114	oxidation reduction
GO:0010942	positive regulation of cell death
GO:0051262	protein tetramerization
GO:0006979	response to oxidative stress
GO:0016259	selenocysteine metabolic process

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005634	nucleus

Molecular Function

GO:0050660	FAD binding
GO:0045340	mercury ion binding
GO:0016174	NAD(P)H oxidase activity
GO:0050661	NADP or NADPH binding
GO:0016491	oxidoreductase activity
GO:0016668	oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
GO:0042803	protein homodimerization activity
GO:0033797	selenate reductase activity
GO:0004791	thioredoxin-disulfide reductase activity

thioredoxin reductase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function