IQ motif containing GTPase activating protein 2

 jump to detail

Synonym

4933417J23Rik, A630053O10, IQ motif containing GTPase activating protein 2, Iqgap2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:60.80 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:- retina:32.10 eye:38 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:1437.70 spleen:158 thymus:118.60 bone marrow:- adipose:212.70 bone:- skin:7.90
GeneChip cerebrum:6.88 cerebellum:5.19 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.75 spine:5.12 retina:7.83 eye:7.46 artery/aorta:- vein:6.83 lymphnode:7.93 peripheral blood:- spleen:6.99 thymus:- bone marrow:8.68 adipose:7.26 bone:7.94 skin:5.71
CAGE cerebrum:1.87 cerebellum:- brain stem:0.83 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.75 retina:- eye:- artery/aorta:2.36 vein:- lymphnode:3.99 peripheral blood:- spleen:2.85 thymus:2.78 bone marrow:- adipose:- bone:3.10 skin:2.79
RNA-seq cerebrum:4.16 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:303.80 prostate:154.40 ovary:114.90 testis:14.80 heart:18.60 muscle:- esophagus:- stomach:130.90 intestine:37 colon:-     liver/hepato:54.30        lung:60.30    bladder:- kidney:80.60 pituitary:- thyroid/parathyroid:- adrenal gland:424.40 pancreas:56.30 breast:55.50 salivary:108
GeneChip uterus:7.75 placenta:8.94 prostate:10.11 ovary:7.23 testis:5.12 heart:5.81 muscle:6.21 esophagus:- stomach:9.41 intestine:10.80 colon:- liver/hepato:10.72 lung:7.03 bladder:6.95 kidney:8.55 pituitary:8.23 thyroid/parathyroid:- adrenal gland:10.70 pancreas:8.44 breast:6.85 salivary:11.09
CAGE uterus:3.92 placenta:3.12 prostate:4.91 ovary:2.34 testis:1.18 heart:- muscle:- esophagus:- stomach:4.03 intestine:5.12 colon:5.44     liver/hepato:5.44    lung:2.80 bladder:2.21 kidney:- pituitary:3.14 thyroid/parathyroid:- adrenal gland:4.84 pancreas:4.21 breast:2.72 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.92 esophagus:- stomach:- intestine:- colon:-     liver/hepato:22.46        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_027711
Gene ID 544963
Unigene ID Mm.38878
Probe set ID 1459894_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021676

Orthologous Gene

Human[1]  NM_006633
Rat[1]  NM_006633

Chromosomal Region

-

Gene Family (Interpro ID)

IPR016146  Calponin-homology
IPR001715  Calponin-like actin-binding
IPR001936  Ras GTPase-activating protein
IPR008936  Rho GTPase activation protein
IPR001202  WW/Rsp5/WWP

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11544199
12466851
12477932
12520002
14516655
14610273
15457341
16141072
16141073
16964442
16966370
18180285
18287559
18604197
21267068
21677750
21931791
21968151
22493426
23951254
24268772

Gene Ontology  (GO ID)

Biological Process

GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007165  signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005622  intracellular
GO:0005874  microtubule
GO:0005902  microvillus

Molecular Function

GO:0005516  calmodulin binding
GO:0005096  GTPase activator activity
GO:0005099  Ras GTPase activator activity