transducer of ERBB2, 2

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Synonym

mKIAA1663, 4930545K18Rik, Tob2 protein, AV071822, transducer of ERBB2, 2, Tob2, Transducer of erbB-2 2, 2900090N22Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:50.40 cerebellum:221 brain stem:95.30 corpus callosum/glia:- pineal gland:- peripheral nerve:133.80 spine:189.10 retina:353.60 eye:114 artery/aorta:759.50 vein:- lymphnode:54 peripheral blood:172.50 spleen:39.50 thymus:217.40 bone marrow:51.30 adipose:212.70 bone:75.10 skin:300.90
GeneChip cerebrum:7.75 cerebellum:8.89 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.21 spine:8.18 retina:9.25 eye:8.45 artery/aorta:- vein:8.18 lymphnode:8.88 peripheral blood:- spleen:9.31 thymus:- bone marrow:8.61 adipose:9.38 bone:8.59 skin:8.82
CAGE cerebrum:3.50 cerebellum:- brain stem:2.77 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.89 retina:- eye:- artery/aorta:5.15 vein:- lymphnode:3.28 peripheral blood:- spleen:2.81 thymus:3.48 bone marrow:- adipose:- bone:3.28 skin:3.87
RNA-seq cerebrum:5.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:- prostate:- ovary:229.80 testis:73.90 heart:37.20 muscle:106.50 esophagus:- stomach:32.70 intestine:- colon:35.20     liver/hepato:298.70        lung:80.30    bladder:330.90 kidney:80.60 pituitary:12.90 thyroid/parathyroid:- adrenal gland:- pancreas:56.30 breast:111 salivary:216
GeneChip uterus:8.87 placenta:8.24 prostate:8.78 ovary:9 testis:7.09 heart:9.82 muscle:9.24 esophagus:- stomach:8.40 intestine:8.79 colon:- liver/hepato:9.19 lung:9.06 bladder:8.59 kidney:9.34 pituitary:9.22 thyroid/parathyroid:- adrenal gland:9.67 pancreas:7 breast:9.46 salivary:8.88
CAGE uterus:3.17 placenta:2.74 prostate:2.95 ovary:2.77 testis:2.05 heart:- muscle:- esophagus:- stomach:2.60 intestine:3.46 colon:3.75     liver/hepato:4.05    lung:3.13 bladder:3.09 kidney:- pituitary:3.59 thyroid/parathyroid:- adrenal gland:3.64 pancreas:3.10 breast:3.88 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:4.92 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.51        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_020507
Gene ID 57259
Unigene ID Mm.323595
Probe set ID 1448667_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000048546

Orthologous Gene

Human[2]  NM_016272
Rat[1]  NM_001007146

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7671812
8889548
10349636
10788617
10940559
11042159
11076861
11217851
11377414
12466851
12477932
12693553
14610273
15489334
16141072
16141073
16602821
16890162
17015433
18358842
18799693
21267068
23071089
23564456

Gene Ontology  (GO ID)

Biological Process

GO:0045671  negative regulation of osteoclast differentiation
GO:0045778  positive regulation of ossification
GO:0010468  regulation of gene expression

Molecular Function

GO:0042809  vitamin D receptor binding