endothelial differentiation-related factor 1

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Synonym

AA409425, EDF-1, Endothelial differentiation-related factor 1, endothelial differentiation-related factor 1, MBF1, Edf1, Multiprotein-bridging factor 1, 0610008L11Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:100.70 cerebellum:55.30 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:- retina:- eye:76 artery/aorta:- vein:- lymphnode:21.60 peripheral blood:71.90 spleen:26.30 thymus:19.80 bone marrow:- adipose:- bone:162.80 skin:87.10
GeneChip cerebrum:9.14 cerebellum:9.36 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.89 spine:9.09 retina:5.99 eye:6.33 artery/aorta:- vein:8.81 lymphnode:9.69 peripheral blood:- spleen:8.99 thymus:- bone marrow:8.72 adipose:10.02 bone:8.48 skin:8.89
CAGE nodata
RNA-seq cerebrum:43.84 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:179.50 prostate:- ovary:23 testis:110.80 heart:93 muscle:177.50 esophagus:- stomach:523.70 intestine:665.50 colon:123.40     liver/hepato:135.80        lung:40.20    bladder:- kidney:161.20 pituitary:51.70 thyroid/parathyroid:337.40 adrenal gland:- pancreas:337.80 breast:75.10 salivary:54
GeneChip uterus:9.14 placenta:9.39 prostate:9.97 ovary:9.26 testis:9.91 heart:9.32 muscle:9.81 esophagus:- stomach:10.17 intestine:10.28 colon:- liver/hepato:10.29 lung:9.29 bladder:9.25 kidney:9.91 pituitary:8.99 thyroid/parathyroid:- adrenal gland:9.34 pancreas:9.30 breast:9.70 salivary:9.29
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:29.41 esophagus:- stomach:- intestine:- colon:-     liver/hepato:59.58        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_021519
Gene ID 59022
Unigene ID Mm.29945
Probe set ID 1448266_at  [Mouse430_2]
Ensembl ID ENSMUSG00000015092

Orthologous Gene

Human[4]  NM_003792, NM_153200
Rat[1]  NM_001106557, NM_153200

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001387  Helix-turn-helix type 3
IPR010982  Lambda repressor-like, DNA-binding

Link to Pubmed  (Pubmed ID)

8889548
10349636
10679242
11042159
11076861
11217851
11587857
12466851
12477932
12958152
14610273
15489334
16141072
16141073
16602821
18287559
19334288
19554257
20059953
23376715

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0007275  multicellular organismal development
GO:0043388  positive regulation of DNA binding
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005669  transcription factor TFIID complex

Molecular Function

GO:0005516  calmodulin binding
GO:0003677  DNA binding
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity