carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

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Synonym

Cpad, 2410008J01Rik, AU018859

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:154.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:96.40 eye:106.40 artery/aorta:- vein:- lymphnode:- peripheral blood:258.80 spleen:- thymus:19.80 bone marrow:- adipose:- bone:50.10 skin:87.10
GeneChip cerebrum:6.45 cerebellum:6.38 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.74 spine:6.88 retina:5.88 eye:5.41 artery/aorta:- vein:7.42 lymphnode:8.18 peripheral blood:- spleen:8.14 thymus:- bone marrow:8.79 adipose:10.11 bone:8.10 skin:6.97
CAGE cerebrum:2.43 cerebellum:- brain stem:2.40 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.68 retina:- eye:- artery/aorta:2.83 vein:- lymphnode:2.91 peripheral blood:- spleen:3.82 thymus:3.21 bone marrow:- adipose:- bone:3.66 skin:2.97
RNA-seq cerebrum:3.94 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:82.80 prostate:30.90 ovary:46 testis:192.10 heart:37.20 muscle:- esophagus:- stomach:32.70 intestine:- colon:52.90     liver/hepato:18.10        lung:50.20    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:84.40 breast:62 salivary:54
GeneChip uterus:7.81 placenta:6.65 prostate:10.08 ovary:7.99 testis:7.27 heart:7.07 muscle:7.21 esophagus:- stomach:7.35 intestine:7.72 colon:- liver/hepato:7.17 lung:7.19 bladder:7.06 kidney:6.47 pituitary:7.97 thyroid/parathyroid:- adrenal gland:6.95 pancreas:8.52 breast:7.40 salivary:7.32
CAGE uterus:3.03 placenta:3.07 prostate:3.29 ovary:3.29 testis:2.89 heart:- muscle:- esophagus:- stomach:1.35 intestine:3.38 colon:2.84     liver/hepato:2.66    lung:2.70 bladder:2.78 kidney:- pituitary:3.14 thyroid/parathyroid:- adrenal gland:2.94 pancreas:3.74 breast:3.11 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.55 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.59        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_023525
Gene ID 69719
Unigene ID Mm.305535
Probe set ID 1452829_at  [Mouse430_2]
Ensembl ID ENSMUSG00000013629

Orthologous Gene

Human[1]  NM_004341
Rat[1]  NM_001105710

Chromosomal Region

-

Gene Family (Interpro ID)

IPR006220  Anthranilate synthase component II/delta crystallin
IPR002082  Aspartate carbamoyltransferase, eukaryotic
IPR006130  Aspartate/ornithine carbamoyltransferase
IPR011761  ATP-grasp fold
IPR001317  Carbamoyl phosphate synthase, GATase domain
IPR000991  Glutamine amidotransferase class-I, C-terminal
IPR011702  Glutamine amidotransferase superfamily
IPR017926  Glutamine amidotransferase type 1
IPR011607  MGS-like

Link to Pubmed  (Pubmed ID)

8889548
9811896
10349636
10725249
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14681479
15735755
16141072
16141073
17510285
20362542
21565611
21677750
22692683
22922362

Gene Ontology  (GO ID)

Biological Process

GO:0006207  'de novo' pyrimidine base biosynthetic process
GO:0017144  drug metabolic process
GO:0018107  peptidyl-threonine phosphorylation
GO:0046777  protein amino acid autophosphorylation
GO:0006228  UTP biosynthetic process

Cellular Component

GO:0042995  cell projection
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016363  nuclear matrix
GO:0005634  nucleus
GO:0043234  protein complex
GO:0043195  terminal button

Molecular Function

GO:0004070  aspartate carbamoyltransferase activity
GO:0005524  ATP binding
GO:0004088  carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004151  dihydroorotase activity
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0004672  protein kinase activity
GO:0016740  transferase activity
GO:0002134  UTP binding