regulator of G-protein signaling 12

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Synonym

1200016K18Rik, regulator of G-protein signaling 12, Rgs12, 4632412M04Rik, E130309H11, AI481290

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:151.10 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:96.40 eye:114 artery/aorta:- vein:- lymphnode:54 peripheral blood:14.40 spleen:105.30 thymus:49.40 bone marrow:12.80 adipose:- bone:37.60 skin:197.90
GeneChip nodata
CAGE cerebrum:2.56 cerebellum:- brain stem:2.52 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.31 retina:- eye:- artery/aorta:1.24 vein:- lymphnode:2.14 peripheral blood:- spleen:3.04 thymus:2.76 bone marrow:- adipose:- bone:2.37 skin:3.57
RNA-seq cerebrum:4.39 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:82.80 prostate:30.90 ovary:46 testis:29.60 heart:279 muscle:- esophagus:- stomach:32.70 intestine:- colon:-     liver/hepato:36.20        lung:100.40    bladder:66.20 kidney:32.20 pituitary:38.80 thyroid/parathyroid:- adrenal gland:848.90 pancreas:18.80 breast:22.90 salivary:-
GeneChip nodata
CAGE uterus:2.73 placenta:2.40 prostate:2.14 ovary:2.73 testis:2.36 heart:- muscle:- esophagus:- stomach:2.79 intestine:1.29 colon:1.72     liver/hepato:0.78    lung:3.48 bladder:3.78 kidney:- pituitary:2.10 thyroid/parathyroid:- adrenal gland:1.72 pancreas:0 breast:1.66 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.28 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.50        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001163512
Gene ID 71729
Unigene ID Mm.196208
Probe set ID -
Ensembl ID ENSMUSG00000029101

Orthologous Gene

Human[9]  NM_002926, NM_198227, NM_198229
Rat [0]  

Chromosomal Region

5B2  [35,292,094  -  35,382,293]

Gene Family (Interpro ID)

IPR006020  Phosphotyrosine interaction domain
IPR011993  Pleckstrin homology-type
IPR000342  Regulator of G protein signalling
IPR016137  Regulator of G protein signalling superfamily

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11829488
12466851
12477932
14610273
15525537
15782199
16141072
16141073
16145674
16602821
17042716
17380122
18799693
21267068
21677750
23349096
24154525

Gene Ontology  (GO ID)

Biological Process

GO:0043547  positive regulation of GTPase activity
GO:0007165  signal transduction

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0001965  G-protein alpha-subunit binding
GO:0005096  GTPase activator activity
GO:0030695  GTPase regulator activity
GO:0005057  receptor signaling protein activity