niacin receptor 1

 jump to detail

Synonym

Gpr109a, G protein-coupled receptor 109A, G-protein coupled receptor HM74, Protein PUMA-G, PUMA-G, Pumag, mHM74b, Nicotinic acid receptor, G-protein coupled receptor 109, Gpr109b, HM74, Gpr109

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:259.20 peripheral blood:57.50 spleen:52.70 thymus:- bone marrow:25.60 adipose:- bone:- skin:15.80
GeneChip cerebrum:4.67 cerebellum:4.86 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.59 spine:4.90 retina:5.08 eye:6.25 artery/aorta:- vein:5.70 lymphnode:5.63 peripheral blood:- spleen:6.46 thymus:- bone marrow:6.14 adipose:7.07 bone:6.18 skin:9.12
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.32 retina:- eye:- artery/aorta:3.51 vein:- lymphnode:1.28 peripheral blood:- spleen:2.49 thymus:1.43 bone marrow:- adipose:- bone:2.37 skin:3.73
RNA-seq cerebrum:0.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.37 placenta:5.61 prostate:5.29 ovary:5.26 testis:4.83 heart:5.73 muscle:5.81 esophagus:- stomach:6.36 intestine:5.10 colon:- liver/hepato:5.55 lung:5.60 bladder:6.33 kidney:5.60 pituitary:4.77 thyroid/parathyroid:- adrenal gland:6.14 pancreas:4.73 breast:6.42 salivary:5.31
CAGE uterus:1.78 placenta:1.42 prostate:0.51 ovary:1.88 testis:0 heart:- muscle:- esophagus:- stomach:2.79 intestine:0.23 colon:0.41     liver/hepato:0.78    lung:2.43 bladder:2.75 kidney:- pituitary:0.29 thyroid/parathyroid:- adrenal gland:1.61 pancreas:0 breast:1.67 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.06 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_030701
Gene ID 80885
Unigene ID Mm.440567
Probe set ID 1419721_at  [Mouse430_2]
Ensembl ID ENSMUSG00000045502

Orthologous Gene

Human[2]  NM_177551, NM_006018
Rat[1]  NM_181476, NM_006018

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
11745392
12466851
12477932
12563315
12646212
15929991
16141072
16141073
16322797
16602821
19136666
19141678
19223991
19561068
20033346
20655299
21267068
21317532
21441844
21774590
22427566
22842580
22914621
23579073
23882124
23967184
24226773
24371223
24412617
24691444

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0050995  negative regulation of lipid catabolic process
GO:0001781  neutrophil apoptosis
GO:0070165  positive regulation of adiponectin secretion
GO:0033031  positive regulation of neutrophil apoptosis
GO:0007165  signal transduction

Cellular Component

GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0005525  GTP binding
GO:0070553  nicotinic acid receptor activity
GO:0001614  purinergic nucleotide receptor activity
GO:0004871  signal transducer activity