phosphoinositide-3-kinase adaptor protein 1

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Synonym

Pik3ap1, BCAP, phosphoinositide-3-kinase adaptor protein 1, 1810044J04Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:280.80 peripheral blood:86.30 spleen:289.70 thymus:- bone marrow:500 adipose:- bone:62.60 skin:7.90
GeneChip cerebrum:5.31 cerebellum:5.38 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.05 spine:5.59 retina:5.58 eye:5.79 artery/aorta:- vein:5.28 lymphnode:7.24 peripheral blood:- spleen:7.32 thymus:- bone marrow:6.45 adipose:5.71 bone:6.05 skin:5
CAGE cerebrum:1.21 cerebellum:- brain stem:1.59 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.70 retina:- eye:- artery/aorta:2.28 vein:- lymphnode:4.12 peripheral blood:- spleen:3.67 thymus:2.44 bone marrow:- adipose:- bone:3.54 skin:2.11
RNA-seq cerebrum:1.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:- prostate:- ovary:23 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:52.90     liver/hepato:-        lung:20.10    bladder:- kidney:- pituitary:64.60 thyroid/parathyroid:- adrenal gland:- pancreas:18.80 breast:52.20 salivary:54
GeneChip uterus:5.86 placenta:6.18 prostate:6.12 ovary:5.44 testis:6.55 heart:5.64 muscle:5.58 esophagus:- stomach:5.62 intestine:5.68 colon:- liver/hepato:7.05 lung:6.09 bladder:5.40 kidney:5.54 pituitary:5.64 thyroid/parathyroid:- adrenal gland:5.22 pancreas:6.86 breast:5.95 salivary:6.46
CAGE uterus:2.81 placenta:2.08 prostate:3.80 ovary:2.48 testis:0 heart:- muscle:- esophagus:- stomach:1.07 intestine:1.49 colon:2.92     liver/hepato:4.30    lung:3.54 bladder:2.27 kidney:- pituitary:1.63 thyroid/parathyroid:- adrenal gland:3.37 pancreas:4.72 breast:2.53 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.32 esophagus:- stomach:- intestine:- colon:-     liver/hepato:6.02        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_031376
Gene ID 83490
Unigene ID Mm.222266
Probe set ID 1421285_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025017

Orthologous Gene

Human[1]  NM_152309
Rat[1]  NM_001106368

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11163197
11217851
11877477
12466851
12477932
12518443
12833156
15102471
16141072
16141073
18025150
18337558
20728433
21677750
21685326
21725061
22187458
22187460
22761313
23913047

Gene Ontology  (GO ID)

Biological Process

GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0034123  positive regulation of toll-like receptor signaling pathway
GO:0043122  regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050727  regulation of inflammatory response
GO:0043408  regulation of MAPKKK cascade
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034154  toll-like receptor 7 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0042802  identical protein binding
GO:0005515  protein binding