purinergic receptor P2X, ligand-gated ion channel, 5

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Synonym

P2rx5, P2X5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.50 cerebellum:- brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:21.60 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.50 skin:7.90
GeneChip cerebrum:5.35 cerebellum:5.48 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.54 spine:7.25 retina:5.85 eye:6.07 artery/aorta:- vein:5.59 lymphnode:5.62 peripheral blood:- spleen:5.61 thymus:- bone marrow:5.18 adipose:7.19 bone:5.43 skin:5.88
CAGE cerebrum:0.30 cerebellum:- brain stem:1.20 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:1.33 retina:- eye:- artery/aorta:3.62 vein:- lymphnode:0.94 peripheral blood:- spleen:0.29 thymus:0.49 bone marrow:- adipose:- bone:0 skin:0.97
RNA-seq cerebrum:1.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:112.50 adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip uterus:5.29 placenta:5.95 prostate:5.83 ovary:5.14 testis:5.89 heart:7.42 muscle:7.26 esophagus:- stomach:5.59 intestine:5.26 colon:- liver/hepato:5.50 lung:5.98 bladder:5.92 kidney:6.76 pituitary:5.55 thyroid/parathyroid:- adrenal gland:6.54 pancreas:6.44 breast:6.43 salivary:5.96
CAGE uterus:0.44 placenta:0.70 prostate:0.51 ovary:0.13 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0.23 colon:0.23     liver/hepato:0    lung:1.11 bladder:1.14 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0.71 pancreas:0 breast:0.74 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.00 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_033321
Gene ID 94045
Unigene ID Mm.156893
Probe set ID 1449433_at  [Mouse430_2]
Ensembl ID ENSMUSG00000005950

Orthologous Gene

Human[2]  NM_001204519, NM_001204520, NM_002561, NM_175080
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001429  P2X purinoreceptor
IPR003048  P2X5 purinoceptor

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
11404011
12466851
12477932
15231720
16141072
16141073
17605080
18657557
18773945
19076210
19442872
21267068
22442090
23271560
24661878

Gene Ontology  (GO ID)

Biological Process

GO:0006812  cation transport
GO:0007166  cell surface receptor linked signal transduction
GO:0034220  ion transmembrane transport
GO:0006811  ion transport
GO:0051260  protein homooligomerization
GO:0019228  regulation of action potential in neuron
GO:0043416  regulation of skeletal muscle tissue regeneration
GO:0006810  transport

Cellular Component

GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0004931  ATP-gated cation channel activity
GO:0008144  drug binding
GO:0005525  GTP binding
GO:0001614  purinergic nucleotide receptor activity
GO:0008270  zinc ion binding