WNK lysine deficient protein kinase 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:35.50 artery/aorta:357.10 vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:195.20 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:199.10 prostate:227.70 ovary:- testis:82.30 heart:310.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:66.50        lung:50.70    bladder:- kidney:255.20 pituitary:236.90 thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_053794
Gene ID 116477
Unigene ID Rn.27409
Probe set ID -
Ensembl ID ENSRNOG00000009956

Orthologous Gene

Human[3]  NM_001184985, NM_014823, NM_018979
Mouse[2]  NM_001185020, NM_001185021, NM_198703

Chromosomal Region

4q42  [156,297,841  -  156,421,820]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

10828064
11498583
12374799
12671053
15057822
15060842
15081430
15242606
15350218
15583131
16083423
16204408
16301342
16376520
16428287
16775035
17194447
18521183
18547946
19644017
20525693
23376100

Gene Ontology  (GO ID)

Biological Process

GO:0006811  ion transport
GO:0033673  negative regulation of kinase activity
GO:0010923  negative regulation of phosphatase activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007243  protein kinase cascade
GO:0050794  regulation of cellular process

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0005524  ATP binding
GO:0000287  magnesium ion binding
GO:0019902  phosphatase binding
GO:0019870  potassium channel inhibitor activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0030291  protein serine/threonine kinase inhibitor activity