myosin light chain kinase 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:- muscle:797.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_057209
Gene ID 117558
Unigene ID Rn.81191
Probe set ID -
Ensembl ID ENSRNOG00000008235

Orthologous Gene

Human[1]  NM_033118
Mouse[1]  NM_001081044

Chromosomal Region

3q41  [143,252,190  -  143,263,223]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

2465691
2839493
9005973
12105199
12748068
12970723
15347643
15962288
15980175
16002744
16260603
16279942
16515842
16799973
16822834
17419808
17991897
18511912
18621396
21209319
22100921

Gene Ontology  (GO ID)

Biological Process

GO:0055007  cardiac muscle cell differentiation
GO:0055008  cardiac muscle tissue morphogenesis
GO:0006936  muscle contraction
GO:0007274  neuromuscular synaptic transmission
GO:0018105  peptidyl-serine phosphorylation
GO:0018107  peptidyl-threonine phosphorylation
GO:0051272  positive regulation of cellular component movement
GO:0031448  positive regulation of fast-twitch skeletal muscle fiber contraction
GO:0010628  positive regulation of gene expression
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0051726  regulation of cell cycle
GO:0043408  regulation of MAPKKK cascade
GO:0006937  regulation of muscle contraction
GO:0032971  regulation of muscle filament sliding
GO:0048168  regulation of neuronal synaptic plasticity
GO:0014816  satellite cell differentiation
GO:0006941  striated muscle contraction
GO:0048489  synaptic vesicle transport
GO:0006833  water transport

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0043197  dendritic spine
GO:0005634  nucleus
GO:0014069  postsynaptic density
GO:0008021  synaptic vesicle
GO:0043195  terminal button

Molecular Function

GO:0005524  ATP binding
GO:0005516  calmodulin binding
GO:0032027  myosin light chain binding
GO:0004687  myosin light chain kinase activity
GO:0004674  protein serine/threonine kinase activity